Septerna, Inc. Common Stock

SEPNNASDAQUSD
39.53 USD
0.77 (1.99%)AT CLOSE (11:59 AM EDT)
39.79
0.25 (0.65%)
POST MARKET (AS OF 07:34 PM EDT)
Post Market
AS OF 07:34 PM EDT
39.79
0.25 (0.65%)
🔴Market: CLOSED

Septerna, Inc. Common Stock (SEPN) is currently trading at $39.57. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". Key drivers include a robust Altman Z-Score, a weak Piotroski F-Score of 0/9, negative Return on Equity, a bullish Golden Cross on the moving averages and bullish moving average alignment. SEPN is fairly valued relative to its sector peers based on current multiples.

Technical & fundamental data as of Aug 6, 2026.

Open?$39.00
High?$40.12
Low?$38.78
Prev. Close?$38.76
Volume?193.7K
Avg. Volume?472.5K
VWAP?$39.35
Rel. Volume?0.41x
Bid / Ask
Bid?$37.50 × 100
Ask?$45.00 × 100
Spread?$7.50
Midpoint?$41.25
Valuation & Ratios
Market Cap?1.8B
Shares Out?45.1M
Float?21.9M
Float %?48.5%
P/E Ratio?N/A
P/B Ratio?4.71
EPS?-$0.80
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Employees
130
Market Cap
1.7B
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2024-10-25
Address
250 EAST GRAND AVENUE, SUITE 65
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bullish(+3/3)
Medium-Term (Wave)? Bullish(+3/3)
Short-Term (Ripple)? Bullish(+2/3)
MA Alignment?Golden Alignment
Full Technical Analysis →
Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?
3
Z-Score?
99
Momentum?
73
Short Sent.?
26
Piotroski F-Score?0/9Weak
Altman Z-Score?5.39Safe
Confidence?45%Low
Full Fundamental Analysis →
Short InterestHigh
Short % of Float?15.32%High
Short Interest?3.4M
Days to Cover?5.7
Free Float21.9M
Avg Daily Volume585.8K
Settlement Date2026-07-15
Financial Health
Current Ratio?4.71Strong
Quick Ratio?4.71Strong
Cash Ratio?0.92Adequate
Debt/Equity?0.00Low
ValuationFAIRLY VALUEDvs 1 peers + S&P 500
Score
67/100
P/E?
N/A
P/B?
Peers
100
S&P
39
4.71FAIR
P/S?
Peers
100
S&P
3
24.66HIGH
P/FCF?
Peers
100
S&P
68
16.7CHEAP
EV/EBITDA?
S&P
97
-25.7CHEAP
EV/Sales?
Peers
100
S&P
3
23.67HIGH
Returns & Efficiency
ROE?
S&P
9
-9.5%WEAK
ROA?
S&P
3
-6.3%WEAK
Cash Flow & Enterprise
FCF?$106.9M
Enterprise Value?$1.7B
Fundamentals ratios updated end of day