36.22 USD
↘ 1.65 (4.36%)LIVE (AS OF 01:13 PM EDT)
Septerna, Inc. Common Stock
SEPNNASDAQ • USD
Market: OPEN
Septerna, Inc. Common Stock (SEPN) is currently trading at $36.22. The technical outlook is "Sell" and the fundamental picture shows "Neutral". Key drivers include a robust Altman Z-Score, a weak Piotroski F-Score of 0/9, negative Return on Equity and a bullish Golden Cross on the moving averages. SEPN is fairly valued relative to its sector peers based on current multiples.
Technical & fundamental data as of Oct 5, 2026.
Open?$37.97
High?$37.97
Low?$36.22
Prev. Close?$37.87
Volume?230.3K
Avg. Volume?343.5K
VWAP?$36.89
Rel. Volume?0.67x
Bid / Ask
Bid?$32.06 × 100
Ask?$42.08 × 100
Spread?$10.02
Midpoint?$37.07
Valuation & Ratios
Market Cap?1.8B
Shares Out?46.7M
Float?29.3M
Float %?62.7%
P/E Ratio?N/A
P/B Ratio?4.57
EPS?-$0.52
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Themes
Employees
130
Market Cap
1.8B
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2024-10-25
Address
250 EAST GRAND AVENUE, SUITE 65
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
Technical OutlookSell
Strong SellNeutralStrong Buy
Long-Term (Tide)?▼ Bearish(-1/3)
Medium-Term (Wave)?▼ Bearish(-1/3)
Short-Term (Ripple)?▼ Bearish(-2/3)
MA Alignment?Mixed
Full Technical Analysis →Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?3
Z-Score?100
Momentum?73
Short Sent.?29
Piotroski F-Score?0/9Weak
Altman Z-Score?5.94Safe
Confidence?45%Low
Short InterestHigh
Short % of Float?9.89%Elevated
Short Interest?2.9M
Days to Cover?9.5
Free Float29.3M
Avg Daily Volume303.5K
Settlement Date2026-09-15
Financial Health
Current Ratio?4.99Strong
Quick Ratio?4.99Strong
Cash Ratio?1.07Strong
Debt/Equity?0.00Low
ValuationFAIRLY VALUEDvs 1 peers + S&P 500
Score67/100
P/E?N/A▾
P/B?4.57FAIR▾
Peers100
S&P40
P/S?17.88HIGH▾
Peers100
S&P3
P/FCF?16.8CHEAP▾
Peers100
S&P67
EV/EBITDA?-30.9CHEAP▾
S&P97
EV/Sales?17.02HIGH▾
Peers100
S&P3
Returns & Efficiency
ROE?-6.3%WEAK▾
S&P10
ROA?-4.3%WEAK▾
S&P3
Cash Flow & Enterprise
FCF?$105.1M
Enterprise Value?$1.7B
Fundamentals ratios updated end of day