40.85 USD
↗ 0.60 (1.48%)PRE MARKET (AS OF 08:35 AM EDT)
Septerna, Inc. Common Stock
SEPNNASDAQ • USD
Market: OPEN
Septerna, Inc. Common Stock (SEPN) is currently trading at $40.85. The technical outlook is "Buy" and the fundamental picture shows "Neutral". Key drivers include a robust Altman Z-Score, a weak Piotroski F-Score of 0/9, negative Return on Equity, a bullish Golden Cross on the moving averages and bullish moving average alignment. SEPN is fairly valued relative to its sector peers based on current multiples.
Technical & fundamental data as of Aug 26, 2026.
Open?$41.38
High?$41.38
Low?$41.10
Prev. Close?$40.25
Volume?2.3K
Avg. Volume?388.4K
VWAP?$41.32
Rel. Volume?0.01x
Bid / Ask
Bid?$34.33 × 100
Ask?$45.73 × 100
Spread?$11.40
Midpoint?$40.03
Valuation & Ratios
Market Cap?1.9B
Shares Out?46.7M
Float?21.9M
Float %?48.5%
P/E Ratio?N/A
P/B Ratio?4.86
EPS?-$0.52
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Themes
Employees
130
Market Cap
1.9B
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2024-10-25
Address
250 EAST GRAND AVENUE, SUITE 65
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
Technical OutlookBuy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+2/3)
Medium-Term (Wave)?– Neutral(0/3)
Short-Term (Ripple)?▼ Bearish(-2/3)
MA Alignment?Golden Alignment
Full Technical Analysis →Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?3
Z-Score?100
Momentum?73
Short Sent.?70
Piotroski F-Score?0/9Weak
Altman Z-Score?6.31Safe
Confidence?45%Low
Short InterestHigh
Short % of Float?13.14%High
Short Interest?2.9M
Days to Cover?5.1
Free Float21.9M
Avg Daily Volume567.9K
Settlement Date2026-08-14
Financial Health
Current Ratio?4.99Strong
Quick Ratio?4.99Strong
Cash Ratio?1.07Strong
Debt/Equity?0.00Low
ValuationFAIRLY VALUEDvs 1 peers + S&P 500
Score67/100
P/E?N/A▾
P/B?4.86FAIR▾
Peers100
S&P38
P/S?19.00HIGH▾
Peers100
S&P3
P/FCF?17.9CHEAP▾
Peers100
S&P63
EV/EBITDA?-33.0CHEAP▾
S&P97
EV/Sales?18.14HIGH▾
Peers100
S&P3
Returns & Efficiency
ROE?-6.3%WEAK▾
S&P10
ROA?-4.3%WEAK▾
S&P3
Cash Flow & Enterprise
FCF?$105.1M
Enterprise Value?$1.8B
Fundamentals ratios updated end of day