41.38 USD
↗ 0.97 (2.40%)AT CLOSE (03:59 PM EDT)
Septerna, Inc. Common Stock
SEPNNASDAQ • USD
41.44
↗ 0.05 (0.13%)
POST MARKET (AS OF 04:12 PM EDT)
Post Market
AS OF 04:12 PM EDT
41.44
↗ 0.05 (0.13%)
Market: OPEN
Septerna, Inc. Common Stock (SEPN) is currently trading at $41.44. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". Key drivers include a robust Altman Z-Score, a weak Piotroski F-Score of 0/9, negative Return on Equity and a bullish Golden Cross on the moving averages. SEPN is fairly valued relative to its sector peers based on current multiples.
Technical & fundamental data as of Oct 23, 2026.
Open?$40.42
High?$41.95
Low?$38.39
Prev. Close?$40.41
Volume?278.5K
Avg. Volume?384.1K
VWAP?$41.31
Rel. Volume?0.72x
Bid / Ask
Bid?$25.84 × 100
Ask?$59.24 × 100
Spread?$33.40
Midpoint?$42.54
Valuation & Ratios
Market Cap?1.9B
Shares Out?46.7M
Float?29.3M
Float %?62.7%
P/E Ratio?N/A
P/B Ratio?4.88
EPS?-$0.52
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Themes
Employees
130
Market Cap
1.9B
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2024-10-25
Address
250 EAST GRAND AVENUE, SUITE 65
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+3/3)
Medium-Term (Wave)?▲ Bullish(+1/3)
Short-Term (Ripple)?▲ Bullish(+2/3)
MA Alignment?Mixed
Full Technical Analysis →Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?3
Z-Score?100
Momentum?73
Short Sent.?29
Piotroski F-Score?0/9Weak
Altman Z-Score?6.34Safe
Confidence?45%Low
Short InterestHigh
Short % of Float?10.58%High
Short Interest?3.1M
Days to Cover?8.8
Free Float29.3M
Avg Daily Volume351.9K
Settlement Date2026-09-30
Financial Health
Current Ratio?4.99Strong
Quick Ratio?4.99Strong
Cash Ratio?1.07Strong
Debt/Equity?0.00Low
ValuationFAIRLY VALUEDvs 1 peers + S&P 500
Score67/100
P/E?N/A▾
P/B?4.88FAIR▾
Peers100
S&P38
P/S?19.08HIGH▾
Peers100
S&P3
P/FCF?18.0CHEAP▾
Peers100
S&P63
EV/EBITDA?-33.1CHEAP▾
S&P97
EV/Sales?18.22HIGH▾
Peers100
S&P3
Returns & Efficiency
ROE?-6.3%WEAK▾
S&P10
ROA?-4.3%WEAK▾
S&P3
Cash Flow & Enterprise
FCF?$105.1M
Enterprise Value?$1.8B
Fundamentals ratios updated end of day