37.34 USD
↗ 2.80 (8.11%)AT CLOSE (11:59 AM EDT)
Septerna, Inc. Common Stock
SEPNNASDAQ • USD
37.24
↘ 0.10 (0.27%)
POST MARKET (AS OF 05:05 PM EDT)
Post Market
AS OF 05:05 PM EDT
37.24
↘ 0.10 (0.27%)
Market: CLOSED
Septerna, Inc. Common Stock (SEPN) is currently trading at $37.34. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". Key drivers include a robust Altman Z-Score, a weak Piotroski F-Score of 0/9, negative Return on Equity, a bullish Golden Cross on the moving averages and bullish moving average alignment. SEPN is fairly valued relative to its sector peers based on current multiples.
Technical & fundamental data as of Jun 26, 2026.
Open?$34.44
High?$37.48
Low?$34.23
Prev. Close?$34.54
Volume?1.5M
Avg. Volume?377.2K
VWAP?$36.62
Rel. Volume?3.92x
Bid / Ask
Bid?$19.56 × 100
Ask?$46.74 × 100
Spread?$27.18
Midpoint?$33.15
Valuation & Ratios
Market Cap?1.7B
Shares Out?45.1M
Float?26.6M
Float %?59.2%
P/E Ratio?N/A
P/B Ratio?4.45
EPS?-$0.80
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Themes
Employees
130
Market Cap
1.6B
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2024-10-25
Address
250 EAST GRAND AVENUE, SUITE 65
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
SOUTH SAN FRANCISCO, CA 94080
Phone: 650-338-3533
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+3/3)
Medium-Term (Wave)?▲ Bullish(+3/3)
Short-Term (Ripple)?▲ Bullish(+2/3)
MA Alignment?Golden Alignment
Full Technical Analysis →Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?3
Z-Score?99
Momentum?73
Short Sent.?34
Piotroski F-Score?0/9Weak
Altman Z-Score?5.19Safe
Confidence?45%Low
Short InterestHigh
Short % of Float?10.03%High
Short Interest?2.7M
Days to Cover?7.8
Free Float26.6M
Avg Daily Volume342.6K
Settlement Date2026-06-15
Financial Health
Current Ratio?4.71Strong
Quick Ratio?4.71Strong
Cash Ratio?0.92Adequate
Debt/Equity?0.00Low
ValuationFAIRLY VALUEDvs 1 peers + S&P 500
Score67/100
P/E?N/A▾
P/B?4.45FAIR▾
Peers100
S&P40
P/S?23.29HIGH▾
Peers100
S&P3
P/FCF?15.7CHEAP▾
Peers100
S&P71
EV/EBITDA?-24.2CHEAP▾
S&P97
EV/Sales?22.30HIGH▾
Peers100
S&P3
Returns & Efficiency
ROE?-9.5%WEAK▾
S&P9
ROA?-6.3%WEAK▾
S&P3
Cash Flow & Enterprise
FCF?$106.9M
Enterprise Value?$1.6B
Fundamentals ratios updated end of day