| Eli Lilly & Co. | Metabolic & Cardiometabolic | $1.0t | $1187.53 | +0.9% | 8.4K | |
| Johnson & Johnson | Immunology & Autoimmune | $0.6t | $261.57 | +0.0% | 8.8K | |
| ABBVIE INC. | Immunology & Autoimmune | $464.4b | $277.74 | +0.6% | 3.4K | |
| Merck & Co., Inc. | Infectious Disease & Vaccines | $356.0b | $145.98 | +0.4% | 16.1K | |
| AstraZeneca PLC | Metabolic & Cardiometabolic | $243.3b | $159.43 | +0.2% | 6.3K | |
| Thermo Fisher Scientific, Inc. | Clinical-Stage Platforms | $242.1b | $658.52 | 0.0% | 273 | |
| Amgen Inc | Rare Disease TherapeuticsImmunology & Autoimmune | $217.9b | $417.38 | 0.0% | 1.7K | |
| Gilead Sciences Inc | Infectious Disease & Vaccines | $179.5b | $151.50 | 0.0% | 1.7K | |
| Pfizer Inc. | Infectious Disease & Vaccines | $158.5b | $28.41 | +0.5% | 122.4K | |
| Vertex Pharmaceuticals Inc | Rare Disease Therapeutics | $127.9b | $513.80 | 0.0% | 715 | |
| Bristol-Myers Squibb Co. | Immunology & Autoimmune | $124.9b | $61.08 | +3.7% | 685.2K | |
| Moderna, Inc. Common Stock | Infectious Disease & Vaccines | $75.9b | $224.22 | 0.0% | 329.2K | |
| Regeneron Pharmaceuticals Inc | Immunology & Autoimmune | $75.7b | $747.45 | 0.0% | 103 | |
| Agilent Technologies Inc. | Clinical-Stage Platforms | $47.3b | $171.62 | -0.3% | 1.6K | |
| IQVIA Holdings Inc. | Clinical-Stage Platforms | $42.5b | $261.00 | 0.0% | 881 | |
| Waters Corp | Clinical-Stage Platforms | $41.8b | $434.00 | 0.0% | 36 | |
| Biogen Inc. Common Stock | Neuroscience & CNS | $32.5b | $233.52 | 0.0% | 20.7K | |
| Alnylam Pharmaceuticals, Inc. | Rare Disease Therapeutics | $29.4b | $234.00 | 0.0% | 268 | |
| Roivant Sciences Ltd. Common Shares | Immunology & Autoimmune | $25.8b | $34.63 | 0.0% | 7.4K | |
| West Pharmaceutical Services, Inc. | Clinical-Stage Platforms | $25.7b | $363.56 | 0.0% | 70 | |
| Royalty Pharma plc Class A Ordinary Shares | Clinical-Stage Platforms | $25.5b | $57.22 | 0.0% | 3 | |
| Insmed, Inc. | Rare Disease Therapeutics | $24.3b | $99.94 | 0.0% | 9.0K | |
| Incyte Genomics Inc | Rare Disease Therapeutics | $23.4b | $112.06 | 0.0% | 160 | |
| United Therapeutics Corp | Rare Disease Therapeutics | $23.2b | $551.16 | 0.0% | 2.5K | |
| Revvity, Inc. | Clinical-Stage Platforms | $16.9b | $153.49 | +0.1% | 2.1K | |
| Medpace Holdings, Inc. Common Stock | Clinical-Stage Platforms | $16.7b | $609.42 | 0.0% | 42 | |
| Jazz Pharmaceuticals, Inc. | Neuroscience & CNS | $15.3b | $219.30 | 0.0% | 414 | |
| Ascendis Pharma A/S Ordinary Share | Clinical-Stage Platforms | $15.0b | $229.13 | 0.0% | 7 | |
| Neurocrine Biosciences Inc | Neuroscience & CNS | $14.6b | $142.25 | 0.0% | 71 | |
| Charles River Laboratories International, Inc. | Clinical-Stage Platforms | $13.9b | $303.05 | 0.0% | 96 | |
| Summit Therapeutics Inc. Common Stock | Infectious Disease & Vaccines | $13.4b | $17.55 | 0.0% | 51.2K | |
| BridgeBio Pharma, Inc. Common Stock | Rare Disease Therapeutics | $13.1b | $66.16 | 0.0% | 637 | |
| Corcept Therapeutics Inc. | Rare Disease Therapeutics | $12.6b | $120.90 | 0.0% | 631 | |
| Twist Bioscience Corporation Common Stock | Clinical-Stage Platforms | $12.5b | $158.03 | 0.0% | 34.7K | |
| Icon Plc | Clinical-Stage Platforms | $12.5b | $164.13 | 0.0% | 1 | |
| Halozyme Therapeutics, Inc. | Clinical-Stage Platforms | $12.5b | $110.78 | 0.0% | 3.2K | |
| Madrigal Pharmaceuticals, Inc. Common Stock | Metabolic & Cardiometabolic | $11.5b | $472.31 | 0.0% | N/A | |
| Bio-Techne Corp. | Clinical-Stage Platforms | $11.4b | $72.29 | 0.0% | 5 | |
| BioMarin Pharmaceuticals Inc | Rare Disease Therapeutics | $11.1b | $55.70 | 0.0% | 10.6K | |
| ImmunityBio, Inc. Common Stock | Immunology & Autoimmune | $10.9b | $10.55 | 0.0% | 52.4K | |
| Avantor, Inc. | Clinical-Stage Platforms | $10.4b | $15.67 | +0.5% | 13.8K | |
| Repligen Corp | Clinical-Stage Platforms | $10.3b | $174.75 | 0.0% | 4.8K | |
| Apogee Therapeutics, Inc. Common Stock | Immunology & Autoimmune | $10.2b | $135.09 | 0.0% | N/A | |
| Bruker Corporation | Clinical-Stage Platforms | $9.6b | $58.91 | 0.0% | 474 | |
| Krystal Biotech, Inc. Common Stock | Rare Disease Therapeutics | $9.5b | $330.74 | 0.0% | 54 | |
| Axsome Therapeutics, Inc | Neuroscience & CNS | $9.4b | $170.01 | 0.0% | 1.4K | |
| QIAGEN N.V. | Clinical-Stage Platforms | $9.2b | $45.67 | +0.7% | 1.8K | |
| Cytokinetics Inc. | Neuroscience & CNSRare Disease Therapeutics | $9.1b | $63.13 | 0.0% | 3.7K | |
| Arrowhead Research Corporation | Rare Disease Therapeutics | $9.1b | $63.16 | 0.0% | 843 | |
| Protagonist Therapeutics, Inc | Immunology & AutoimmuneMetabolic & Cardiometabolic | $9.1b | $144.00 | 0.0% | 2.6K |