| Eli Lilly & Co. | Targeted Therapy & Precision Oncology | $1.0t | $1211.50 | +7.4% | 5.3M | |
| Johnson & Johnson | Immunotherapy & Immuno-Oncology | $0.5t | $254.38 | +4.0% | 9.7M | |
| ABBVIE INC. | Immunotherapy & Immuno-Oncology | $384.7b | $252.95 | +4.1% | 11.1M | |
| Merck & Co., Inc. | Immunotherapy & Immuno-Oncology | $293.2b | $128.22 | +1.7% | 9.8M | |
| AstraZeneca PLC | Immunotherapy & Immuno-Oncology | $287.9b | $188.18 | +1.5% | 2.5M | |
| Amgen Inc | Immunotherapy & Immuno-Oncology | $181.8b | $357.17 | +1.4% | 1.7M | |
| Gilead Sciences Inc | Cell & Gene Therapy for Cancer | $166.9b | $127.40 | +2.8% | 7.2M | |
| Bristol-Myers Squibb Co. | Immunotherapy & Immuno-Oncology | $116.8b | $57.40 | +3.8% | 9.2M | |
| Regeneron Pharmaceuticals Inc | Immunotherapy & Immuno-Oncology | $64.5b | $629.25 | +2.1% | 689.1K | |
| Revolution Medicines, Inc. Common Stock | Targeted Therapy & Precision Oncology | $33.5b | $182.99 | +2.2% | 2.9M | |
| Natera, Inc. Common Stock | Cancer Diagnostics & Biomarkers | $32.0b | $261.00 | -0.0% | 2.2M | |
| Royalty Pharma plc Class A Ordinary Shares | Immunotherapy & Immuno-Oncology | $24.7b | $55.59 | +2.9% | 4.4M | |
| Incyte Genomics Inc | Targeted Therapy & Precision Oncology | $19.3b | $112.75 | +5.8% | 2.2M | |
| Moderna, Inc. Common Stock | Immunotherapy & Immuno-Oncology | $18.7b | $67.14 | +12.6% | 12.8M | |
| Guardant Health, Inc. Common Stock | Cancer Diagnostics & Biomarkers | $17.2b | $150.70 | +4.5% | 3.7M | |
| Jazz Pharmaceuticals, Inc. | Targeted Therapy & Precision Oncology | $14.8b | $229.94 | +1.7% | 517.2K | |
| Exelixis Inc | Targeted Therapy & Precision Oncology | $12.7b | $54.90 | +3.0% | 1.8M | |
| Nuvalent, Inc. Class A Common Stock | Targeted Therapy & Precision Oncology | $8.7b | $123.85 | -0.0% | 1.6M | |
| Halozyme Therapeutics, Inc. | Targeted Therapy & Precision Oncology | $7.9b | $75.08 | +3.2% | 1.7M | |
| ImmunityBio, Inc. Common Stock | Immunotherapy & Immuno-Oncology | $7.9b | $8.48 | +11.6% | 23.1M | |
| Corcept Therapeutics Inc. | Targeted Therapy & Precision Oncology | $7.5b | $86.66 | +3.1% | 616.3K | |
| Arcellx, Inc. Common Stock | Immunotherapy & Immuno-OncologyCell & Gene Therapy for Cancer | $6.7b | $115.06 | -0.0% | 16.1M | |
| Celcuity Inc. Common Stock | Targeted Therapy & Precision Oncology | $6.5b | $99.14 | +4.2% | 1.2M | |
| Lantheus Holdings, Inc | Radiopharmaceuticals & ADCs | $6.5b | $109.25 | +0.6% | 899.0K | |
| Cogent Biosciences, Inc. Common Stock | Targeted Therapy & Precision Oncology | $6.0b | $38.20 | +0.0% | 3.1M | |
| CG Oncology, Inc. Common stock | Immunotherapy & Immuno-Oncology | $5.5b | $72.01 | -1.3% | 1.4M | |
| Caris Life Sciences, Inc. Common Stock | Cancer Diagnostics & Biomarkers | $4.7b | $18.71 | -1.0% | 4.0M | |
| BillionToOne, Inc. Class A Common Stock | Cancer Diagnostics & Biomarkers | $4.6b | $118.06 | +5.1% | 896.9K | |
| Erasca, Inc. Common Stock | Targeted Therapy & Precision Oncology | $4.0b | $16.05 | +6.9% | 7.7M | |
| Veracyte, Inc. | Cancer Diagnostics & Biomarkers | $3.7b | $60.50 | +3.3% | 1.1M | |
| Arcus Biosciences, Inc. | Immunotherapy & Immuno-Oncology | $3.2b | $31.36 | +2.5% | 1.6M | |
| Tango Therapeutics, Inc. | Targeted Therapy & Precision Oncology | $3.2b | $30.50 | +4.3% | 6.0M | |
| GRAIL, Inc. Common Stock | Cancer Diagnostics & Biomarkers | $3.1b | $65.97 | -1.1% | 401.6K | |
| Relay Therapeutics, Inc. Common Stock | Targeted Therapy & Precision Oncology | $3.1b | $18.67 | +3.9% | 4.0M | |
| IDEAYA Biosciences, Inc. Common Stock | Targeted Therapy & Precision Oncology | $2.6b | $35.44 | +1.2% | 1.7M | |
| Enliven Therapeutics, Inc. Common Stock | Targeted Therapy & Precision Oncology | $2.5b | $50.07 | +2.0% | 3.3M | |
| Immunome, Inc. | Targeted Therapy & Precision OncologyRadiopharmaceuticals & ADCs | $2.5b | $19.87 | +3.0% | 1.6M | |
| Adaptive Biotechnologies Corporation Common Stock | Cancer Diagnostics & Biomarkers | $2.4b | $21.02 | +3.4% | 2.7M | |
| Day One Biopharmaceuticals, Inc. Common Stock | Targeted Therapy & Precision Oncology | $2.2b | $21.52 | -0.0% | 3.0M | |
| Nektar Therapeutics | Immunotherapy & Immuno-Oncology | $2.2b | $63.62 | +2.4% | 1.1M | |
| Tyra Biosciences, Inc. Common Stock | Targeted Therapy & Precision Oncology | $2.0b | $31.91 | +3.0% | 1.3M | |
| NovoCure Limited Ordinary Shares | Targeted Therapy & Precision Oncology | $2.0b | $15.31 | +2.7% | 877.1K | |
| Intellia Therapeutics, Inc | Cell & Gene Therapy for Cancer | $2.0b | $16.63 | +3.9% | 4.4M | |
| AbCellera Biologics Inc. Common Shares | Radiopharmaceuticals & ADCs | $1.9b | $7.40 | +10.7% | 13.6M | |
| Zymeworks Inc. | Targeted Therapy & Precision Oncology | $1.8b | $24.42 | +1.6% | 390.1K | |
| Nurix Therapeutics, Inc. Common stock | Targeted Therapy & Precision Oncology | $1.8b | $22.35 | +2.0% | 2.9M | |
| Iovance Biotherapeutics, Inc. Common Stock | Cell & Gene Therapy for CancerImmunotherapy & Immuno-Oncology | $1.8b | $4.24 | +0.4% | 10.9M | |
| Syndax Pharmaceuticals, Inc. | Immunotherapy & Immuno-Oncology | $1.7b | $21.15 | +7.6% | 2.0M | |
| SELLAS Life Sciences Group, Inc. Common Stock | Immunotherapy & Immuno-Oncology | $1.7b | $12.21 | +17.7% | 15.4M | |
| Monte Rosa Therapeutics, Inc. Common Stock | Targeted Therapy & Precision Oncology | $1.7b | $22.23 | +2.9% | 1.6M |