| AstraZeneca PLC | Precision Medicine Platforms | $243.3b | $170.69 | -0.6% | 158.1K | |
| Thermo Fisher Scientific, Inc. | Precision Medicine Platforms | $242.1b | $676.39 | -0.4% | 1.6M | |
| Danaher Corporation | Precision Medicine Platforms | $150.5b | $230.67 | +0.3% | 335.9K | |
| Vertex Pharmaceuticals Inc | Gene Therapy & Gene Editing | $127.9b | $524.88 | -2.1% | 64.2K | |
| Regeneron Pharmaceuticals Inc | Gene Therapy & Gene Editing | $75.7b | $805.50 | -1.7% | 431.7K | |
| Natera, Inc. Common Stock | Genetic Testing & Diagnostics | $59.1b | $405.96 | +0.7% | 1.0M | |
| Waters Corp | Precision Medicine Platforms | $41.8b | $454.91 | -0.4% | 794.6K | |
| Illumina Inc | Genetic Testing & Diagnostics | $41.2b | $269.50 | -0.1% | 1.0M | |
| Alnylam Pharmaceuticals, Inc. | RNA Therapeutics | $29.4b | $226.08 | -1.5% | 800.2K | |
| Labcorp Holdings Inc. | Genetic Testing & Diagnostics | $25.0b | $329.39 | -0.3% | 487.3K | |
| Insmed, Inc. | Gene Therapy & Gene Editing | $24.3b | $93.82 | -1.7% | 2.5M | |
| Guardant Health, Inc. Common Stock | Precision Medicine Platforms | $23.9b | $171.24 | +3.6% | 1.5M | |
| Revvity, Inc. | Precision Medicine Platforms | $16.9b | $158.79 | +0.9% | 903.1K | |
| Tempus AI, Inc. Class A Common Stock | Precision Medicine Platforms | $13.9b | $67.10 | +6.0% | 3.9M | |
| BridgeBio Pharma, Inc. Common Stock | Precision Medicine Platforms | $13.1b | $68.57 | +0.6% | 2.0M | |
| Twist Bioscience Corporation Common Stock | Precision Medicine Platforms | $12.5b | $138.77 | +3.2% | 1.6M | |
| 10x Genomics, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $12.2b | $71.37 | +2.4% | 1.9M | |
| Bio-Techne Corp. | Precision Medicine Platforms | $11.4b | $72.64 | -0.1% | 1.4M | |
| BioMarin Pharmaceuticals Inc | Gene Therapy & Gene Editing | $11.1b | $55.95 | -1.1% | 1.3M | |
| Bio-Rad Laboratories, Inc.Class A | Genetic Testing & Diagnostics | $10.1b | $369.94 | +1.8% | 19.2K | |
| Nuvalent, Inc. Class A Common Stock | Precision Medicine Platforms | $9.8b | $123.96 | 0.0% | N/A | |
| Krystal Biotech, Inc. Common Stock | Gene Therapy & Gene Editing | $9.5b | $314.55 | -2.7% | 190.7K | |
| QIAGEN N.V. | Genetic Testing & Diagnostics | $9.2b | $50.38 | +0.3% | 6.5M | |
| Arrowhead Research Corporation | RNA Therapeutics | $9.1b | $58.06 | -0.6% | 668.0K | |
| Kymera Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $8.9b | $112.48 | -0.1% | 92.4K | |
| Praxis Precision Medicines, Inc. Common Stock | Precision Medicine Platforms | $8.3b | $252.81 | -2.4% | 322.0K | |
| Caris Life Sciences, Inc. Common Stock | Precision Medicine Platforms | $8.0b | $32.07 | +0.9% | 170.5K | |
| Ionis Pharmaceuticals, Inc. Common Stock | RNA Therapeutics | $7.2b | $43.34 | -2.3% | 2.4M | |
| Lantheus Holdings, Inc | Precision Medicine Platforms | $6.5b | $99.81 | -0.3% | 76.5K | |
| CRISPR Therapeutics AG | Gene Therapy & Gene Editing | $5.4b | $49.30 | -1.2% | 76.0K | |
| BillionToOne, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $5.0b | $104.77 | +2.1% | 433.0K | |
| Amicus Therapeutics, Inc | Gene Therapy & Gene Editing | $4.5b | $14.49 | +0.0% | 3.5M | |
| Adaptive Biotechnologies Corporation Common Stock | Precision Medicine Platforms | $4.5b | $24.87 | +4.5% | 1.6M | |
| Veracyte, Inc. | Genetic Testing & Diagnostics | $3.7b | $48.02 | +4.1% | 626.3K | |
| IDEAYA Biosciences, Inc. Common Stock | Precision Medicine Platforms | $3.6b | $34.70 | -4.0% | 83.3K | |
| CareDx, Inc. | Precision Medicine PlatformsGenetic Testing & Diagnostics | $3.5b | $69.42 | +0.0% | 77.5K | |
| Precigen, Inc. Common Stock | Gene Therapy & Gene Editing | $3.1b | $6.19 | -3.1% | 3.8M | |
| Dyne Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $2.8b | $15.60 | -1.1% | 1.6M | |
| Beam Therapeutics Inc. Common Stock | Gene Therapy & Gene Editing | $2.5b | $23.80 | -2.2% | 1.2M | |
| NeoGenomics, Inc. | Genetic Testing & Diagnostics | $2.4b | $16.59 | +1.2% | 1.1M | |
| Alamar Biosciences, Inc. Common Stock | Precision Medicine Platforms | $2.2b | $30.71 | +3.2% | 645.0K | |
| GeneDx Holdings Corp. Class A Common Stock | Genetic Testing & DiagnosticsPrecision Medicine Platforms | $2.2b | $61.36 | -14.3% | 2.3M | |
| Vericel Corporation | Gene Therapy & Gene Editing | $2.1b | $42.52 | -1.0% | 409.4K | |
| Sarepta Therapeutics,, Inc. Common Stock | Gene Therapy & Gene Editing | $1.8b | $17.66 | -2.6% | 931.3K | |
| BioLife Solutions Inc. | Gene Therapy & Gene Editing | $1.8b | $38.60 | 0.0% | N/A | |
| Personalis, Inc. Common Stock | Genetic Testing & Diagnostics | $1.7b | $15.60 | +0.2% | 126.3K | |
| Intellia Therapeutics, Inc | Gene Therapy & Gene Editing | $1.7b | $11.13 | +0.4% | 2.7M | |
| Azenta, Inc. | Genetic Testing & Diagnostics | $1.7b | $36.50 | +1.3% | 362.2K | |
| uniQure N.V. | Gene Therapy & Gene Editing | $1.6b | $23.02 | -3.0% | 772.6K | |
| Taysha Gene Therapies, Inc. Common Stock | Gene Therapy & Gene Editing | $1.5b | $3.88 | -1.0% | 2.1M |