| AstraZeneca PLC | Precision Medicine Platforms | $250.7b | $157.08 | -0.2% | 1.6M | |
| Thermo Fisher Scientific, Inc. | Precision Medicine Platforms | $228.7b | $668.27 | +3.4% | 1.6M | |
| Danaher Corporation | Precision Medicine Platforms | $147.6b | $217.34 | +3.3% | 2.6M | |
| Vertex Pharmaceuticals Inc | Gene Therapy & Gene Editing | $141.4b | $504.62 | -0.2% | 457.3K | |
| Regeneron Pharmaceuticals Inc | Gene Therapy & Gene Editing | $86.8b | $733.58 | -1.2% | 515.0K | |
| Natera, Inc. Common Stock | Genetic Testing & Diagnostics | $47.2b | $424.67 | +3.7% | 1.7M | |
| Waters Corp | Precision Medicine Platforms | $40.6b | $442.70 | +3.5% | 772.5K | |
| Alnylam Pharmaceuticals, Inc. | RNA Therapeutics | $35.8b | $219.85 | +0.1% | 950.8K | |
| Illumina Inc | Genetic Testing & Diagnostics | $32.2b | $294.00 | +7.6% | 3.1M | |
| Insmed, Inc. | Gene Therapy & Gene Editing | $27.7b | $105.04 | -6.6% | 4.8M | |
| Labcorp Holdings Inc. | Genetic Testing & Diagnostics | $26.9b | $306.10 | +0.1% | 523.8K | |
| Guardant Health, Inc. Common Stock | Precision Medicine Platforms | $21.9b | $189.00 | +5.4% | 1.5M | |
| BridgeBio Pharma, Inc. Common Stock | Precision Medicine Platforms | $15.0b | $66.55 | -1.6% | 1.7M | |
| Revvity, Inc. | Precision Medicine Platforms | $14.6b | $157.31 | +4.2% | 1.1M | |
| BioMarin Pharmaceuticals Inc | Gene Therapy & Gene Editing | $13.0b | $57.55 | +0.7% | 1.8M | |
| Arrowhead Research Corporation | RNA Therapeutics | $12.1b | $62.99 | -2.8% | 1.6M | |
| Tempus AI, Inc. Class A Common Stock | Precision Medicine Platforms | $11.7b | $83.30 | +9.1% | 6.2M | |
| Bio-Techne Corp. | Precision Medicine Platforms | $11.4b | $72.61 | +0.3% | 1.6M | |
| Krystal Biotech, Inc. Common Stock | Gene Therapy & Gene Editing | $10.9b | $334.89 | +3.9% | 231.2K | |
| Ionis Pharmaceuticals, Inc. Common Stock | RNA Therapeutics | $10.2b | $43.79 | -0.1% | 2.0M | |
| Praxis Precision Medicines, Inc. Common Stock | Precision Medicine Platforms | $9.9b | $279.87 | -4.0% | 403.4K | |
| Kymera Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $9.9b | $109.74 | +2.2% | 544.8K | |
| Nuvalent, Inc. Class A Common Stock | Precision Medicine Platforms | $9.8b | $123.96 | 0.0% | N/A | |
| QIAGEN N.V. | Genetic Testing & Diagnostics | $9.1b | $45.78 | +2.8% | 2.4M | |
| Twist Bioscience Corporation Common Stock | Precision Medicine Platforms | $8.5b | $207.16 | +8.8% | 2.3M | |
| 10x Genomics, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $8.2b | $98.15 | +4.7% | 2.4M | |
| Caris Life Sciences, Inc. Common Stock | Precision Medicine Platforms | $7.0b | $30.02 | +7.4% | 3.6M | |
| Lantheus Holdings, Inc | Precision Medicine Platforms | $6.6b | $100.19 | +0.2% | 456.8K | |
| CRISPR Therapeutics AG | Gene Therapy & Gene Editing | $5.5b | $56.29 | +3.2% | 1.4M | |
| Dyne Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $4.7b | $15.63 | +1.6% | 3.7M | |
| BillionToOne, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $4.5b | $110.99 | +3.0% | 368.8K | |
| Amicus Therapeutics, Inc | Gene Therapy & Gene Editing | $4.5b | $14.49 | +0.0% | 3.5M | |
| Adaptive Biotechnologies Corporation Common Stock | Precision Medicine Platforms | $3.9b | $29.76 | +5.3% | 1.1M | |
| IDEAYA Biosciences, Inc. Common Stock | Precision Medicine Platforms | $3.9b | $38.10 | +1.9% | 481.2K | |
| Veracyte, Inc. | Genetic Testing & Diagnostics | $3.6b | $47.77 | +4.0% | 928.8K | |
| uniQure N.V. | Gene Therapy & Gene Editing | $3.1b | $22.75 | -2.8% | 2.6M | |
| Beam Therapeutics Inc. Common Stock | Gene Therapy & Gene Editing | $3.0b | $25.71 | +4.9% | 1.6M | |
| GeneDx Holdings Corp. Class A Common Stock | Precision Medicine PlatformsGenetic Testing & Diagnostics | $2.6b | $76.35 | +4.1% | 477.8K | |
| CareDx, Inc. | Genetic Testing & DiagnosticsPrecision Medicine Platforms | $2.6b | $70.00 | +4.0% | 1.3M | |
| Precigen, Inc. Common Stock | Gene Therapy & Gene Editing | $2.6b | $7.77 | -9.4% | 9.3M | |
| Sarepta Therapeutics,, Inc. Common Stock | Gene Therapy & Gene Editing | $2.4b | $17.39 | 0.0% | 1.7M | |
| NeoGenomics, Inc. | Genetic Testing & Diagnostics | $2.2b | $18.36 | +3.6% | 1.3M | |
| Vericel Corporation | Gene Therapy & Gene Editing | $2.1b | $41.89 | +2.3% | 460.9K | |
| Taysha Gene Therapies, Inc. Common Stock | Gene Therapy & Gene Editing | $1.8b | $4.49 | -3.0% | 2.4M | |
| Personalis, Inc. Common Stock | Genetic Testing & Diagnostics | $1.8b | $16.43 | +0.9% | 948.3K | |
| Intellia Therapeutics, Inc | Gene Therapy & Gene Editing | $1.8b | $12.68 | +4.2% | 4.5M | |
| BioLife Solutions Inc. | Gene Therapy & Gene Editing | $1.8b | $38.60 | +3.5% | 3.9M | |
| Alto Neuroscience Inc. | Precision Medicine Platforms | $1.4b | $24.00 | -3.2% | 431.4K | |
| Maze Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $1.4b | $25.88 | +0.1% | 484.7K | |
| Azenta, Inc. | Genetic Testing & Diagnostics | $1.4b | $43.70 | +10.3% | 2.0M |