| AstraZeneca PLC | Precision Medicine Platforms | $287.9b | $185.00 | +1.5% | 1.7M | |
| Thermo Fisher Scientific, Inc. | Precision Medicine Platforms | $183.0b | $510.97 | +2.9% | 2.3M | |
| Danaher Corporation | Precision Medicine Platforms | $129.3b | $191.94 | +2.3% | 5.0M | |
| Vertex Pharmaceuticals Inc | Gene Therapy & Gene Editing | $113.6b | $483.08 | +1.0% | 1.0M | |
| Regeneron Pharmaceuticals Inc | Gene Therapy & Gene Editing | $64.5b | $623.00 | -0.6% | 548.8K | |
| Alnylam Pharmaceuticals, Inc. | RNA Therapeutics | $40.3b | $289.33 | -0.3% | 968.9K | |
| Waters Corp | Precision Medicine Platforms | $37.7b | $375.90 | +2.1% | 742.7K | |
| Natera, Inc. Common Stock | Genetic Testing & Diagnostics | $32.0b | $264.89 | +0.2% | 2.2M | |
| Illumina Inc | Genetic Testing & Diagnostics | $24.7b | $177.95 | +1.4% | 2.6M | |
| Insmed, Inc. | Gene Therapy & Gene Editing | $23.2b | $105.92 | +1.0% | 3.6M | |
| Labcorp Holdings Inc. | Genetic Testing & Diagnostics | $21.3b | $266.27 | +0.4% | 366.4K | |
| Guardant Health, Inc. Common Stock | Precision Medicine Platforms | $17.2b | $144.81 | +4.3% | 2.2M | |
| BridgeBio Pharma, Inc. Common Stock | Precision Medicine Platforms | $13.0b | $69.70 | +0.5% | 2.4M | |
| Ionis Pharmaceuticals, Inc. Common Stock | RNA Therapeutics | $12.6b | $78.70 | +2.3% | 2.3M | |
| Revvity, Inc. | Precision Medicine Platforms | $11.7b | $113.56 | +7.5% | 1.9M | |
| BioMarin Pharmaceuticals Inc | Gene Therapy & Gene Editing | $11.1b | $56.22 | +0.1% | 1.1M | |
| Arrowhead Research Corporation | RNA Therapeutics | $11.0b | $79.25 | -0.7% | 1.8M | |
| Praxis Precision Medicines, Inc. Common Stock | Precision Medicine Platforms | $9.8b | $320.40 | +6.0% | 709.4K | |
| Krystal Biotech, Inc. Common Stock | Gene Therapy & Gene Editing | $9.1b | $361.56 | +3.5% | 290.6K | |
| Tempus AI, Inc. Class A Common Stock | Precision Medicine Platforms | $9.1b | $54.78 | +5.6% | 8.7M | |
| Nuvalent, Inc. Class A Common Stock | Precision Medicine Platforms | $8.7b | $123.64 | -0.0% | 1.1M | |
| Bio-Techne Corp. | Precision Medicine Platforms | $8.1b | $70.88 | +20.0% | 50.2M | |
| QIAGEN N.V. | Genetic Testing & Diagnostics | $7.5b | $38.95 | +0.5% | 2.8M | |
| Kymera Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $6.7b | $118.90 | +16.5% | 3.7M | |
| Lantheus Holdings, Inc | Precision Medicine Platforms | $6.5b | $109.97 | +3.9% | 719.2K | |
| CRISPR Therapeutics AG | Gene Therapy & Gene Editing | $5.4b | $54.50 | +0.8% | 1.9M | |
| Caris Life Sciences, Inc. Common Stock | Precision Medicine Platforms | $4.7b | $18.83 | +3.0% | 3.3M | |
| BillionToOne, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $4.6b | $112.50 | +4.1% | 809.9K | |
| Amicus Therapeutics, Inc | Gene Therapy & Gene Editing | $4.5b | $14.49 | +0.0% | 3.5M | |
| Twist Bioscience Corporation Common Stock | Precision Medicine Platforms | $4.2b | $97.13 | +5.9% | 2.4M | |
| Veracyte, Inc. | Genetic Testing & Diagnostics | $3.7b | $58.88 | +3.2% | 983.4K | |
| 10x Genomics, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $3.6b | $36.07 | +3.2% | 2.5M | |
| Beam Therapeutics Inc. Common Stock | Gene Therapy & Gene Editing | $3.4b | $34.53 | +0.2% | 1.8M | |
| Dyne Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $3.2b | $20.59 | +1.4% | 1.4M | |
| IDEAYA Biosciences, Inc. Common Stock | Precision Medicine Platforms | $2.6b | $36.28 | +0.1% | 1.0M | |
| Adaptive Biotechnologies Corporation Common Stock | Precision Medicine Platforms | $2.4b | $20.35 | +4.6% | 3.6M | |
| Intellia Therapeutics, Inc | Gene Therapy & Gene Editing | $2.0b | $16.02 | +3.4% | 2.9M | |
| Sarepta Therapeutics,, Inc. Common Stock | Gene Therapy & Gene Editing | $1.9b | $16.11 | -4.1% | 2.2M | |
| uniQure N.V. | Gene Therapy & Gene Editing | $1.8b | $49.46 | +0.5% | 2.4M | |
| Vericel Corporation | Gene Therapy & Gene Editing | $1.7b | $42.83 | +2.8% | 463.6K | |
| Taysha Gene Therapies, Inc. Common Stock | Gene Therapy & Gene Editing | $1.7b | $6.34 | -10.5% | 10.7M | |
| Precigen, Inc. Common Stock | Gene Therapy & Gene Editing | $1.5b | $5.59 | +2.6% | 4.7M | |
| GeneDx Holdings Corp. Class A Common Stock | Precision Medicine PlatformsGenetic Testing & Diagnostics | $1.5b | $68.19 | +8.1% | 990.7K | |
| Maze Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $1.5b | $27.00 | +1.3% | 1.1M | |
| NeoGenomics, Inc. | Genetic Testing & Diagnostics | $1.4b | $13.55 | +6.3% | 3.8M | |
| Wave Life Sciences Ltd. Ordinary Shares | RNA Therapeutics | $1.3b | $5.92 | -3.4% | 2.8M | |
| BioLife Solutions Inc. | Gene Therapy & Gene Editing | $1.2b | $27.23 | +7.5% | 1.8M | |
| Personalis, Inc. Common Stock | Genetic Testing & Diagnostics | $1.2b | $12.75 | +10.9% | 4.7M | |
| CareDx, Inc. | Genetic Testing & DiagnosticsPrecision Medicine Platforms | $1.2b | $28.26 | +2.6% | 1.1M | |
| Opko Health Inc. | Genetic Testing & Diagnostics | $1.1b | $1.47 | +1.3% | 1.6M |