| AstraZeneca PLC | Precision Medicine Platforms | $250.7b | $162.67 | -0.6% | 12.5K | |
| Thermo Fisher Scientific, Inc. | Precision Medicine Platforms | $228.7b | $620.52 | +0.2% | 213 | |
| Danaher Corporation | Precision Medicine Platforms | $147.6b | $203.22 | -0.2% | 230 | |
| Vertex Pharmaceuticals Inc | Gene Therapy & Gene Editing | $141.4b | $519.19 | 0.0% | 223 | |
| Regeneron Pharmaceuticals Inc | Gene Therapy & Gene Editing | $86.8b | $787.83 | 0.0% | 20 | |
| Natera, Inc. Common Stock | Genetic Testing & Diagnostics | $47.2b | $342.35 | 0.0% | 175 | |
| Waters Corp | Precision Medicine Platforms | $40.6b | $408.86 | 0.0% | 1.0K | |
| Alnylam Pharmaceuticals, Inc. | RNA Therapeutics | $35.8b | $247.41 | 0.0% | 287 | |
| Illumina Inc | Genetic Testing & Diagnostics | $32.2b | $202.68 | 0.0% | 139 | |
| Insmed, Inc. | Gene Therapy & Gene Editing | $27.7b | $125.81 | 0.0% | 9 | |
| Labcorp Holdings Inc. | Genetic Testing & Diagnostics | $26.9b | $314.63 | 0.0% | N/A | |
| Guardant Health, Inc. Common Stock | Precision Medicine Platforms | $21.9b | $167.26 | 0.0% | 5 | |
| BridgeBio Pharma, Inc. Common Stock | Precision Medicine Platforms | $15.0b | $72.25 | 0.0% | 105.2K | |
| Revvity, Inc. | Precision Medicine Platforms | $14.6b | $128.68 | 0.0% | 38 | |
| BioMarin Pharmaceuticals Inc | Gene Therapy & Gene Editing | $13.0b | $66.45 | 0.0% | 20 | |
| Arrowhead Research Corporation | RNA Therapeutics | $12.1b | $80.48 | 0.0% | 22 | |
| Tempus AI, Inc. Class A Common Stock | Precision Medicine Platforms | $11.7b | $60.93 | 0.0% | 29.8K | |
| Bio-Techne Corp. | Precision Medicine Platforms | $11.4b | $71.36 | 0.0% | 250 | |
| Krystal Biotech, Inc. Common Stock | Gene Therapy & Gene Editing | $10.9b | $344.54 | 0.0% | 10 | |
| Ionis Pharmaceuticals, Inc. Common Stock | RNA Therapeutics | $10.2b | $51.54 | 0.0% | 4.2K | |
| Praxis Precision Medicines, Inc. Common Stock | Precision Medicine Platforms | $9.9b | $332.27 | 0.0% | 1.3K | |
| Kymera Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $9.9b | $114.25 | 0.0% | 3.8K | |
| Nuvalent, Inc. Class A Common Stock | Precision Medicine Platforms | $9.8b | $123.96 | 0.0% | N/A | |
| QIAGEN N.V. | Genetic Testing & Diagnostics | $9.1b | $42.09 | +0.5% | 2.2K | |
| Twist Bioscience Corporation Common Stock | Precision Medicine Platforms | $8.5b | $132.87 | 0.0% | 630 | |
| 10x Genomics, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $8.2b | $69.13 | 0.0% | 1.4K | |
| Caris Life Sciences, Inc. Common Stock | Precision Medicine Platforms | $7.0b | $25.70 | 0.0% | 120 | |
| Lantheus Holdings, Inc | Precision Medicine Platforms | $6.6b | $100.25 | 0.0% | 163 | |
| CRISPR Therapeutics AG | Gene Therapy & Gene Editing | $5.5b | $52.40 | 0.0% | 2.0K | |
| Dyne Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $4.7b | $18.53 | 0.0% | 805 | |
| BillionToOne, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $4.5b | $100.91 | 0.0% | 19 | |
| Amicus Therapeutics, Inc | Gene Therapy & Gene Editing | $4.5b | $14.49 | +0.0% | 3.5M | |
| Adaptive Biotechnologies Corporation Common Stock | Precision Medicine Platforms | $3.9b | $24.85 | 0.0% | N/A | |
| IDEAYA Biosciences, Inc. Common Stock | Precision Medicine Platforms | $3.9b | $38.04 | 0.0% | 177 | |
| Veracyte, Inc. | Genetic Testing & Diagnostics | $3.6b | $41.05 | 0.0% | 92 | |
| uniQure N.V. | Gene Therapy & Gene Editing | $3.1b | $45.51 | 0.0% | 542 | |
| Beam Therapeutics Inc. Common Stock | Gene Therapy & Gene Editing | $3.0b | $24.07 | 0.0% | 3.4K | |
| GeneDx Holdings Corp. Class A Common Stock | Precision Medicine PlatformsGenetic Testing & Diagnostics | $2.6b | $88.48 | 0.0% | 311 | |
| CareDx, Inc. | Genetic Testing & DiagnosticsPrecision Medicine Platforms | $2.6b | $52.35 | 0.0% | 45 | |
| Precigen, Inc. Common Stock | Gene Therapy & Gene Editing | $2.6b | $6.85 | 0.0% | 68 | |
| Sarepta Therapeutics,, Inc. Common Stock | Gene Therapy & Gene Editing | $2.4b | $20.71 | 0.0% | 165 | |
| NeoGenomics, Inc. | Genetic Testing & Diagnostics | $2.2b | $18.40 | 0.0% | 80 | |
| Vericel Corporation | Gene Therapy & Gene Editing | $2.1b | $39.77 | 0.0% | 4 | |
| Taysha Gene Therapies, Inc. Common Stock | Gene Therapy & Gene Editing | $1.8b | $5.02 | 0.0% | 15 | |
| Personalis, Inc. Common Stock | Genetic Testing & Diagnostics | $1.8b | $16.36 | 0.0% | 70 | |
| Intellia Therapeutics, Inc | Gene Therapy & Gene Editing | $1.8b | $11.92 | 0.0% | 7.4K | |
| BioLife Solutions Inc. | Gene Therapy & Gene Editing | $1.8b | $35.54 | 0.0% | 211 | |
| Alto Neuroscience Inc. | Precision Medicine Platforms | $1.4b | $32.05 | 0.0% | N/A | |
| Maze Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $1.4b | $24.66 | 0.0% | N/A | |
| Azenta, Inc. | Genetic Testing & Diagnostics | $1.4b | $31.70 | 0.0% | 16.3K |