| AstraZeneca PLC | Precision Medicine Platforms | $263.1b | $169.90 | +2.0% | 1.1M | |
| Thermo Fisher Scientific, Inc. | Precision Medicine Platforms | $212.2b | $625.09 | -0.4% | 589.1K | |
| Danaher Corporation | Precision Medicine Platforms | $137.1b | $214.47 | +0.2% | 719.2K | |
| Vertex Pharmaceuticals Inc | Gene Therapy & Gene Editing | $119.5b | $554.15 | +1.2% | 150.1K | |
| Regeneron Pharmaceuticals Inc | Gene Therapy & Gene Editing | $78.2b | $836.51 | +1.3% | 198.1K | |
| Natera, Inc. Common Stock | Genetic Testing & Diagnostics | $38.7b | $333.06 | +1.9% | 968.9K | |
| Waters Corp | Precision Medicine Platforms | $36.8b | $411.98 | +0.6% | 137.8K | |
| Illumina Inc | Genetic Testing & Diagnostics | $31.0b | $224.29 | +0.9% | 394.1K | |
| Alnylam Pharmaceuticals, Inc. | RNA Therapeutics | $27.5b | $239.08 | +1.1% | 422.7K | |
| Labcorp Holdings Inc. | Genetic Testing & Diagnostics | $25.0b | $334.08 | -1.5% | 213.2K | |
| Guardant Health, Inc. Common Stock | Precision Medicine Platforms | $21.7b | $166.51 | +2.1% | 391.7K | |
| Insmed, Inc. | Gene Therapy & Gene Editing | $21.4b | $125.50 | +1.6% | 408.0K | |
| BridgeBio Pharma, Inc. Common Stock | Precision Medicine Platforms | $15.7b | $80.76 | -0.2% | 351.0K | |
| Revvity, Inc. | Precision Medicine Platforms | $12.9b | $124.19 | +1.3% | 171.8K | |
| Arrowhead Research Corporation | RNA Therapeutics | $11.9b | $88.81 | +2.6% | 281.2K | |
| BioMarin Pharmaceuticals Inc | Gene Therapy & Gene Editing | $11.6b | $66.05 | +1.8% | 279.8K | |
| Bio-Techne Corp. | Precision Medicine Platforms | $11.2b | $72.33 | -0.1% | 831.9K | |
| Krystal Biotech, Inc. Common Stock | Gene Therapy & Gene Editing | $10.1b | $353.77 | +3.6% | 52.5K | |
| Nuvalent, Inc. Class A Common Stock | Precision Medicine Platforms | $9.8b | $123.96 | 0.0% | N/A | |
| QIAGEN N.V. | Genetic Testing & Diagnostics | $8.7b | $42.86 | +2.8% | 969.0K | |
| Ionis Pharmaceuticals, Inc. Common Stock | RNA Therapeutics | $8.6b | $63.86 | +2.9% | 935.3K | |
| Praxis Precision Medicines, Inc. Common Stock | Precision Medicine Platforms | $8.5b | $367.26 | +0.1% | 125.1K | |
| Kymera Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $8.5b | $124.22 | +2.9% | 138.5K | |
| Tempus AI, Inc. Class A Common Stock | Precision Medicine Platforms | $8.3b | $69.72 | +5.3% | 4.6M | |
| Lantheus Holdings, Inc | Precision Medicine Platforms | $6.5b | $100.99 | +0.2% | 313.0K | |
| BillionToOne, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $6.4b | $97.78 | +1.0% | 252.2K | |
| Twist Bioscience Corporation Common Stock | Precision Medicine Platforms | $6.3b | $152.43 | +8.7% | 600.3K | |
| 10x Genomics, Inc. Class A Common Stock | Genetic Testing & Diagnostics | $6.0b | $65.85 | +4.0% | 1.2M | |
| CRISPR Therapeutics AG | Gene Therapy & Gene Editing | $4.7b | $60.99 | +7.4% | 982.1K | |
| Dyne Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $4.7b | $26.20 | +1.0% | 492.5K | |
| Amicus Therapeutics, Inc | Gene Therapy & Gene Editing | $4.5b | $14.49 | +0.0% | 3.5M | |
| Caris Life Sciences, Inc. Common Stock | Precision Medicine Platforms | $4.4b | $27.24 | +3.5% | 1.7M | |
| Veracyte, Inc. | Genetic Testing & Diagnostics | $3.6b | $42.96 | +3.7% | 219.3K | |
| Adaptive Biotechnologies Corporation Common Stock | Precision Medicine Platforms | $3.6b | $26.28 | +2.9% | 363.5K | |
| IDEAYA Biosciences, Inc. Common Stock | Precision Medicine Platforms | $3.4b | $41.81 | +4.6% | 299.0K | |
| uniQure N.V. | Gene Therapy & Gene Editing | $3.1b | $49.55 | +5.4% | 839.7K | |
| Beam Therapeutics Inc. Common Stock | Gene Therapy & Gene Editing | $2.6b | $31.18 | +10.1% | 695.0K | |
| Vericel Corporation | Gene Therapy & Gene Editing | $2.4b | $43.05 | +1.1% | 120.3K | |
| Precigen, Inc. Common Stock | Gene Therapy & Gene Editing | $2.4b | $7.36 | +2.4% | 1.5M | |
| CareDx, Inc. | Genetic Testing & DiagnosticsPrecision Medicine Platforms | $2.3b | $49.64 | +4.4% | 673.9K | |
| NeoGenomics, Inc. | Genetic Testing & Diagnostics | $2.0b | $16.75 | +2.0% | 179.2K | |
| GeneDx Holdings Corp. Class A Common Stock | Genetic Testing & DiagnosticsPrecision Medicine Platforms | $2.0b | $87.51 | +2.6% | 211.8K | |
| Sarepta Therapeutics,, Inc. Common Stock | Gene Therapy & Gene Editing | $1.7b | $18.88 | +4.7% | 393.0K | |
| Taysha Gene Therapies, Inc. Common Stock | Gene Therapy & Gene Editing | $1.7b | $6.21 | +4.4% | 308.4K | |
| BioLife Solutions Inc. | Gene Therapy & Gene Editing | $1.5b | $37.25 | +0.4% | 153.5K | |
| Maze Therapeutics, Inc. Common Stock | Precision Medicine Platforms | $1.5b | $30.59 | +3.0% | 116.3K | |
| Intellia Therapeutics, Inc | Gene Therapy & Gene Editing | $1.5b | $13.59 | +8.6% | 1.6M | |
| Personalis, Inc. Common Stock | Genetic Testing & Diagnostics | $1.4b | $17.39 | +2.2% | 1.2M | |
| Azenta, Inc. | Genetic Testing & Diagnostics | $1.3b | $33.77 | +2.2% | 229.6K | |
| Wave Life Sciences Ltd. Ordinary Shares | RNA Therapeutics | $1.1b | $5.29 | +3.6% | 684.9K |