143.50 USD
↗ 0.10 (0.07%)LIVE (AS OF 02:28 PM EDT)
Protagonist Therapeutics, Inc
PTGXNASDAQ • USD
Market: OPEN
Shares of Protagonist Therapeutics, Inc (PTGX) are trading at $143.50. The technical outlook is "Sell" and the fundamental picture shows "Neutral". Notable factors include a robust Altman Z-Score and a bullish Golden Cross on the moving averages. Valuation-wise, the stock is priced at a premium — multiples like P/E and EV/EBITDA sit above sector averages.
Technical & fundamental data as of Sep 15, 2026.
Open?$144.19
High?$146.12
Low?$142.69
Prev. Close?$143.40
Volume?157.8K
Avg. Volume?514.4K
VWAP?$144.01
Rel. Volume?0.31x
Bid / Ask
Bid?$142.59 × 100
Ask?$143.35 × 100
Spread?$0.76
Midpoint?$142.97
Valuation & Ratios
Market Cap?9.3B
Shares Out?64.7M
Float?58.7M
Float %?90.8%
P/E Ratio?111.92
P/B Ratio?11.03
EPS?$1.28
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
Themes
Employees
141
Market Cap
9.3B
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2016-08-11
Address
7707 GATEWAY BLVD., SUITE 140
NEWARK, CA 94560-1160
Phone: (510) 474-0170
NEWARK, CA 94560-1160
Phone: (510) 474-0170
Technical OutlookSell
Strong SellNeutralStrong Buy
Long-Term (Tide)?– Neutral(0/3)
Medium-Term (Wave)?– Neutral(0/3)
Short-Term (Ripple)?▼ Bearish(-3/3)
MA Alignment?Mixed
Full Technical Analysis →Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?40
Z-Score?100
Momentum?90
Short Sent.?48
Piotroski F-Score?4/9Mixed
Altman Z-Score?127.63Safe
Confidence?63%Moderate
Short InterestVery High
Short % of Float?13.13%High
Short Interest?7.7M
Days to Cover?15.3
Free Float58.7M
Avg Daily Volume502.8K
Settlement Date2026-08-31
Financial Health
Current Ratio?21.71Strong
Quick Ratio?21.71Strong
Cash Ratio?11.30Strong
Debt/Equity?0.00Low
ValuationRICHLY VALUEDvs 1 peers + S&P 500
Score33/100
P/E?111.9PRICEY▾
Peers100
S&P3
P/B?11.03HIGH▾
Peers100
S&P18
P/S?32.91HIGH▾
Peers100
S&P3
P/FCF?N/A▾
EV/EBITDA?148.9HIGH▾
Peers100
S&P3
EV/Sales?31.42HIGH▾
Peers100
S&P3
Returns & Efficiency
ROE?9.9%FAIR▾
Peers50
S&P34
ROA?9.4%STRONG▾
Peers50
S&P72
Cash Flow & Enterprise
FCF?$-88302000
Enterprise Value?$8.9B
Fundamentals ratios updated end of day