Protagonist Therapeutics, Inc

PTGXNASDAQ • USD
140.32 USD
↗ 1.89 (1.37%)AT CLOSE (03:59 PM EDT)
141.14
↗ 0.82 (0.59%)
POST MARKET (AS OF 05:34 PM EDT)
Post Market
AS OF 05:34 PM EDT
141.14
↗ 0.82 (0.59%)
🟢Market: OPEN

Shares of Protagonist Therapeutics, Inc (PTGX) are trading at $141.14. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". Notable factors include a robust Altman Z-Score and a bullish Golden Cross on the moving averages. Valuation-wise, the stock is priced at a premium — multiples like P/E and EV/EBITDA sit above sector averages.

Technical & fundamental data as of Oct 26, 2026.

Open?$139.24
High?$142.00
Low?$137.30
Prev. Close?$138.43
Volume?823.3K
Avg. Volume?799.8K
VWAP?$140.66
Rel. Volume?1.03x
Bid / Ask
Bid?$104.66 × 100
Ask?$159.39 × 100
Spread?$54.73
Midpoint?$132.02
Valuation & Ratios
Market Cap?9.0B
Shares Out?64.7M
Float?61.2M
Float %?94.6%
P/E Ratio?108.04
P/B Ratio?10.64
EPS?$1.28
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
Employees
141
Market Cap
9.0B
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2016-08-11
Address
7707 GATEWAY BLVD., SUITE 140
NEWARK, CA 94560-1160
Phone: (510) 474-0170
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+2/3)
Medium-Term (Wave)?▲ Bullish(+1/3)
Short-Term (Ripple)?▲ Bullish(+3/3)
MA Alignment?Mixed
Full Technical Analysis →
Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?
40
Z-Score?
100
Momentum?
90
Short Sent.?
14
Piotroski F-Score?4/9Mixed
Altman Z-Score?123.24Safe
Confidence?55%Low
Full Fundamental Analysis →
Short InterestVery High
Short % of Float?16.82%High
Short Interest?10.3M
Days to Cover?12.0
Free Float61.2M
Avg Daily Volume856.4K
Settlement Date2026-10-15
Financial Health
Current Ratio?21.71Strong
Quick Ratio?21.71Strong
Cash Ratio?11.30Strong
Debt/Equity?0.00Low
ValuationRICHLY VALUEDvs 1 peers + S&P 500
Score
33/100
P/E?
Peers
100
S&P
3
108.0PRICEY▾
P/B?
Peers
100
S&P
18
10.64HIGH▾
P/S?
Peers
100
S&P
3
31.77HIGH▾
P/FCF?
N/A▾
EV/EBITDA?
Peers
100
S&P
3
143.5HIGH▾
EV/Sales?
Peers
100
S&P
3
30.28HIGH▾
Returns & Efficiency
ROE?
Peers
50
S&P
34
9.9%FAIR▾
ROA?
Peers
50
S&P
72
9.4%STRONG▾
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$8.5B
Fundamentals ratios updated end of day