138.69 USD
↘ 1.94 (1.38%)AT CLOSE (03:59 PM EDT)
Protagonist Therapeutics, Inc
PTGXNASDAQ • USD
138.71
↗ 0.02 (0.01%)
POST MARKET (AS OF 05:52 PM EDT)
Post Market
AS OF 05:52 PM EDT
138.71
↗ 0.02 (0.01%)
Market: OPEN
Shares of Protagonist Therapeutics, Inc (PTGX) are trading at $138.71. The technical outlook is "Sell" and the fundamental picture shows "Neutral". Notable factors include a robust Altman Z-Score and a bullish Golden Cross on the moving averages. Valuation-wise, the stock is priced at a premium — multiples like P/E and EV/EBITDA sit above sector averages.
Technical & fundamental data as of Oct 6, 2026.
Open?$140.34
High?$141.00
Low?$136.09
Prev. Close?$140.63
Volume?635.7K
Avg. Volume?678.9K
VWAP?$138.30
Rel. Volume?0.94x
Bid / Ask
Bid?$119.09 × 100
Ask?$157.11 × 100
Spread?$38.02
Midpoint?$138.10
Valuation & Ratios
Market Cap?9.1B
Shares Out?64.7M
Float?58.7M
Float %?90.8%
P/E Ratio?109.76
P/B Ratio?10.81
EPS?$1.28
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
Themes
Employees
141
Market Cap
9.1B
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2016-08-11
Address
7707 GATEWAY BLVD., SUITE 140
NEWARK, CA 94560-1160
Phone: (510) 474-0170
NEWARK, CA 94560-1160
Phone: (510) 474-0170
Technical OutlookSell
Strong SellNeutralStrong Buy
Long-Term (Tide)?▼ Bearish(-1/3)
Medium-Term (Wave)?▼ Bearish(-1/3)
Short-Term (Ripple)?▼ Bearish(-3/3)
MA Alignment?Mixed
Full Technical Analysis →Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?40
Z-Score?100
Momentum?90
Short Sent.?23
Piotroski F-Score?4/9Mixed
Altman Z-Score?125.19Safe
Confidence?56%Low
Short InterestVery High
Short % of Float?13.86%High
Short Interest?8.1M
Days to Cover?15.1
Free Float58.7M
Avg Daily Volume538.0K
Settlement Date2026-09-15
Financial Health
Current Ratio?21.71Strong
Quick Ratio?21.71Strong
Cash Ratio?11.30Strong
Debt/Equity?0.00Low
ValuationRICHLY VALUEDvs 1 peers + S&P 500
Score33/100
P/E?109.8PRICEY▾
Peers100
S&P3
P/B?10.81HIGH▾
Peers100
S&P18
P/S?32.27HIGH▾
Peers100
S&P3
P/FCF?N/A▾
EV/EBITDA?145.9HIGH▾
Peers100
S&P3
EV/Sales?30.78HIGH▾
Peers100
S&P3
Returns & Efficiency
ROE?9.9%FAIR▾
Peers50
S&P34
ROA?9.4%STRONG▾
Peers50
S&P72
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$8.7B
Fundamentals ratios updated end of day