Protagonist Therapeutics, Inc

PTGXNASDAQ • USD
ThemeBiotech - Drug Development›Metabolic & Cardiometabolic
121.88 USD
↘ 0.75 (0.61%)AT CLOSE (11:59 AM EDT)
121.83
↘ 0.05 (0.04%)
POST MARKET (AS OF 06:04 PM EDT)
Post Market
AS OF 06:04 PM EDT
121.83
↘ 0.05 (0.04%)
🔴Market: CLOSED

Shares of Protagonist Therapeutics, Inc (PTGX) are trading at $121.88. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". Notable factors include a robust Altman Z-Score, negative Return on Equity, a bullish Golden Cross on the moving averages and bullish moving average alignment. Valuation-wise, the stock is priced at a premium — multiples like P/E and EV/EBITDA sit above sector averages.

Technical & fundamental data as of Jun 26, 2026.

Open?$122.00
High?$123.43
Low?$118.31
Prev. Close?$122.63
Volume?2.6M
Avg. Volume?729.7K
VWAP?$121.48
Rel. Volume?3.55x
Bid / Ask
Bid?$100.68 × 100
Ask?$138.95 × 100
Spread?$38.27
Midpoint?$119.82
Valuation & Ratios
Market Cap?7.8B
Shares Out?64.3M
Float?59.7M
Float %?93.6%
P/E Ratio?N/A
P/B Ratio?11.96
EPS?-$1.78
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
Themes
Biotech - Drug Development›Metabolic & CardiometabolicBiotech - Drug Development›Immunology & Autoimmune
Employees
131
Market Cap
7.9B
Industry
PHARMACEUTICAL PREPARATIONS
Website
www.protagonist-inc.com
Listed
2016-08-11
Address
7707 GATEWAY BLVD., SUITE 140
NEWARK, CA 94560-1160
Phone: (510) 474-0170
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+2/3)
Medium-Term (Wave)?▲ Bullish(+2/3)
Short-Term (Ripple)?– Neutral(0/3)
MA Alignment?Golden Alignment
Full Technical Analysis →
Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?
40
Z-Score?
100
Momentum?
23
Short Sent.?
48
Piotroski F-Score?4/9Mixed
Altman Z-Score?111.50Safe
Confidence?57%Low
Full Fundamental Analysis →
Short InterestVery High
Short % of Float?12.94%High
Short Interest?7.7M
Days to Cover?11.6
Free Float59.7M
Avg Daily Volume666.6K
Settlement Date2026-06-15
Financial Health
Current Ratio?17.76Strong
Quick Ratio?17.76Strong
Cash Ratio?5.61Strong
Debt/Equity?0.00Low
ValuationRICHLY VALUEDvs 1 peers + S&P 500
Score
50/100
P/E?
N/A▾
P/B?
Peers
100
S&P
16
11.96HIGH▾
P/S?
Peers
100
S&P
3
105.83HIGH▾
P/FCF?
N/A▾
EV/EBITDA?
S&P
97
-54.2CHEAP▾
EV/Sales?
Peers
100
S&P
3
103.22HIGH▾
Returns & Efficiency
ROE?
S&P
8
-17.5%WEAK▾
ROA?
S&P
3
-16.5%WEAK▾
Cash Flow & Enterprise
FCF?$-117895000
Enterprise Value?$7.6B
Fundamentals ratios updated end of day
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