Protagonist Therapeutics, Inc

PTGXNASDAQ • USD
ThemeBiotech - Drug Development›Metabolic & Cardiometabolic
146.18 USD
↗ 8.86 (6.45%)AT CLOSE (11:59 AM EDT)
143.35
↘ 2.83 (1.94%)
POST MARKET (AS OF 07:57 PM EDT)
Post Market
AS OF 07:57 PM EDT
143.35
↘ 2.83 (1.94%)
🔴Market: CLOSED

Shares of Protagonist Therapeutics, Inc (PTGX) are trading at $146.33. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". Notable factors include a robust Altman Z-Score, negative Return on Equity, a bullish Golden Cross on the moving averages and bullish moving average alignment. Valuation-wise, the stock is priced at a premium — multiples like P/E and EV/EBITDA sit above sector averages.

Technical & fundamental data as of Aug 6, 2026.

Open?$145.01
High?$148.00
Low?$139.95
Prev. Close?$137.32
Volume?837.6K
Avg. Volume?761.0K
VWAP?$145.23
Rel. Volume?1.10x
Bid / Ask
Bid?$120.35 × 100
Ask?$171.99 × 100
Spread?$51.64
Midpoint?$146.17
Valuation & Ratios
Market Cap?8.8B
Shares Out?64.3M
Float?59.7M
Float %?93.6%
P/E Ratio?N/A
P/B Ratio?13.47
EPS?-$1.78
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
Themes
Biotech - Drug Development›Metabolic & CardiometabolicBiotech - Drug Development›Immunology & Autoimmune
Employees
131
Market Cap
8.8B
Industry
PHARMACEUTICAL PREPARATIONS
Website
www.protagonist-inc.com
Listed
2016-08-11
Address
7707 GATEWAY BLVD., SUITE 140
NEWARK, CA 94560-1160
Phone: (510) 474-0170
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+2/3)
Medium-Term (Wave)?▲ Bullish(+1/3)
Short-Term (Ripple)?▲ Bullish(+2/3)
MA Alignment?Golden Alignment
Full Technical Analysis →
Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?
40
Z-Score?
100
Momentum?
23
Short Sent.?
29
Piotroski F-Score?4/9Mixed
Altman Z-Score?125.69Safe
Confidence?57%Low
Full Fundamental Analysis →
Short InterestHigh
Short % of Float?13.89%High
Short Interest?8.3M
Days to Cover?9.5
Free Float59.7M
Avg Daily Volume870.4K
Settlement Date2026-07-15
Financial Health
Current Ratio?17.76Strong
Quick Ratio?17.76Strong
Cash Ratio?5.61Strong
Debt/Equity?0.00Low
ValuationRICHLY VALUEDvs 1 peers + S&P 500
Score
50/100
P/E?
N/A▾
P/B?
Peers
100
S&P
14
13.47HIGH▾
P/S?
Peers
100
S&P
3
119.24HIGH▾
P/FCF?
N/A▾
EV/EBITDA?
S&P
97
-61.3CHEAP▾
EV/Sales?
Peers
100
S&P
3
116.62HIGH▾
Returns & Efficiency
ROE?
S&P
8
-17.5%WEAK▾
ROA?
S&P
3
-16.5%WEAK▾
Cash Flow & Enterprise
FCF?$-117895000
Enterprise Value?$8.6B
Fundamentals ratios updated end of day
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