Spero Therapeutics, Inc. Common Stock

SPRONASDAQUSD
1.22 USD
0.01 (0.81%)AT CLOSE (11:59 AM EDT)
1.22
0.00 (0.41%)
POST MARKET (AS OF 06:59 PM EDT)
Post Market
AS OF 06:59 PM EDT
1.22
0.00 (0.41%)
🟢Market: OPEN

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $1.22 per share. Technical and fundamental signals converge bearishtechnicals rate "Strong Sell" while fundamentals read "Sell". This is driven by a concerning Altman Z-Score in the distress zone, a weak Piotroski F-Score of 1/9, exceptional Return on Equity (28.8%), a bearish Death Cross on the long-term moving averages and bearish long-term moving average alignment. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Aug 26, 2026.

Open?$1.22
High?$1.23
Low?$1.20
Prev. Close?$1.23
Volume?154.8K
Avg. Volume?1.4M
VWAP?$1.21
Rel. Volume?0.11x
Bid / Ask
Bid?$1.04 × 100
Ask?$1.43 × 100
Spread?$0.39
Midpoint?$1.23
Valuation & Ratios
Market Cap?71.6M
Shares Out?58.2M
Float?42.1M
Float %?72.7%
P/E Ratio?4.70
P/B Ratio?1.35
EPS?$0.26
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
71.6M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookStrong Sell
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bearish(-2/3)
Medium-Term (Wave)? Bearish(-1/3)
Short-Term (Ripple)? Bearish(-3/3)
MA Alignment?Bearish Alignment
Full Technical Analysis →
Fundamental OutlookSell
Strong SellNeutralStrong Buy
F-Score?
6
Z-Score?
1
Momentum?
50
Short Sent.?
75
Piotroski F-Score?1/9Weak
Altman Z-Score?-0.96Distress
Confidence?48%Low
Full Fundamental Analysis →
Short InterestLow
Short % of Float?3.43%Low
Short Interest?1.4M
Days to Cover?1.9
Free Float42.1M
Avg Daily Volume760.5K
Settlement Date2026-08-14
Financial Health
Current Ratio?10.50Strong
Quick Ratio?10.50Strong
Cash Ratio?10.23Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
100/100
P/E?
Peers
100
S&P
97
4.7CHEAP
P/B?
Peers
100
S&P
90
1.35CHEAP
P/S?
Peers
100
S&P
84
1.17CHEAP
P/FCF?
Peers
100
S&P
89
9.9CHEAP
EV/EBITDA?
Peers
100
S&P
97
1.1CHEAP
EV/Sales?
Peers
100
S&P
97
0.25CHEAP
Returns & Efficiency
ROE?
Peers
50
S&P
78
28.8%STRONG
ROA?
Peers
50
S&P
97
25.8%STRONG
Cash Flow & Enterprise
FCF?$7.2M
Enterprise Value?$15.6M
Fundamentals ratios updated end of day