Spero Therapeutics, Inc. Common Stock

SPRONASDAQUSD
1.27 USD
0.01 (0.79%)AT CLOSE (11:59 AM EDT)
1.27
0.01 (0.39%)
POST MARKET (AS OF 07:48 PM EDT)
Post Market
AS OF 07:48 PM EDT
1.27
0.01 (0.39%)
🔴Market: CLOSED

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $1.26 per share. Technical and fundamental signals converge bearishtechnicals rate "Sell" while fundamentals read "Sell". This is driven by a concerning Altman Z-Score in the distress zone, a weak Piotroski F-Score of 1/9, exceptional Return on Equity (28.8%), a bearish Death Cross on the long-term moving averages and bearish long-term moving average alignment. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Aug 6, 2026.

Open?$1.26
High?$1.28
Low?$1.23
Prev. Close?$1.26
Volume?974.7K
Avg. Volume?1.8M
VWAP?$1.26
Rel. Volume?0.53x
Bid / Ask
Bid?$1.25 × 200
Ask?$1.28 × 300
Spread?$0.03
Midpoint?$1.27
Valuation & Ratios
Market Cap?73.0M
Shares Out?57.9M
Float?42.1M
Float %?72.7%
P/E Ratio?4.79
P/B Ratio?1.38
EPS?$0.26
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
73.0M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookSell
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bearish(-2/3)
Medium-Term (Wave)? Neutral(0/3)
Short-Term (Ripple)? Bullish(+2/3)
MA Alignment?Bearish Alignment
Full Technical Analysis →
Fundamental OutlookSell
Strong SellNeutralStrong Buy
F-Score?
6
Z-Score?
1
Momentum?
50
Short Sent.?
91
Piotroski F-Score?1/9Weak
Altman Z-Score?-0.83Distress
Confidence?46%Low
Full Fundamental Analysis →
Short InterestElevated
Short % of Float?5.02%Elevated
Short Interest?2.1M
Days to Cover?1.3
Free Float42.1M
Avg Daily Volume1.6M
Settlement Date2026-07-15
Financial Health
Current Ratio?10.50Strong
Quick Ratio?10.50Strong
Cash Ratio?10.23Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
100/100
P/E?
Peers
100
S&P
97
4.8CHEAP
P/B?
Peers
100
S&P
90
1.38CHEAP
P/S?
Peers
100
S&P
84
1.19CHEAP
P/FCF?
N/A
EV/EBITDA?
Peers
100
S&P
97
1.2CHEAP
EV/Sales?
Peers
100
S&P
97
0.28CHEAP
Returns & Efficiency
ROE?
Peers
50
S&P
78
28.8%STRONG
ROA?
Peers
50
S&P
97
25.8%STRONG
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$16.9M
Fundamentals ratios updated end of day