Spero Therapeutics, Inc. Common Stock

SPRONASDAQUSD
1.12 USD
0.01 (1.33%)🟢PRE MARKET (AS OF 07:45 PM EDT)
🟢Market: OPEN

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $1.12 per share. Technical and fundamental signals converge bearishtechnicals rate "Strong Sell" while fundamentals read "Sell". This is driven by a concerning Altman Z-Score in the distress zone, a weak Piotroski F-Score of 0/9, a bearish Death Cross on the long-term moving averages and bearish long-term moving average alignment. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Sep 15, 2026.

Open?$1.14
High?$1.18
Low?$1.12
Prev. Close?$1.13
Volume?215.5K
Avg. Volume?467.6K
VWAP?$1.13
Rel. Volume?0.46x
Bid / Ask
Bid?$0.95 × 100
Ask?$1.28 × 100
Spread?$0.33
Midpoint?$1.12
Valuation & Ratios
Market Cap?65.8M
Shares Out?58.2M
Float?42.1M
Float %?72.7%
P/E Ratio?8.91
P/B Ratio?1.49
EPS?$0.13
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
66.4M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookStrong Sell
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bearish(-2/3)
Medium-Term (Wave)? Bearish(-1/3)
Short-Term (Ripple)? Bearish(-3/3)
MA Alignment?Bearish Alignment
Full Technical Analysis →
Fundamental OutlookSell
Strong SellNeutralStrong Buy
F-Score?
3
Z-Score?
0
Momentum?
10
Short Sent.?
94
Piotroski F-Score?0/9Weak
Altman Z-Score?-5.55Distress
Confidence?43%Low
Full Fundamental Analysis →
Short InterestLow
Short % of Float?2.87%Low
Short Interest?1.2M
Days to Cover?3.0
Free Float42.1M
Avg Daily Volume409.8K
Settlement Date2026-08-31
Financial Health
Current Ratio?6.12Strong
Quick Ratio?6.12Strong
Cash Ratio?6.02Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
100/100
P/E?
Peers
100
S&P
97
8.9CHEAP
P/B?
Peers
100
S&P
87
1.49CHEAP
P/S?
Peers
100
S&P
80
1.40CHEAP
P/FCF?
Peers
100
S&P
97
3.4CHEAP
EV/EBITDA?
Peers
100
S&P
97
2.3CHEAP
EV/Sales?
Peers
100
S&P
97
0.32CHEAP
Returns & Efficiency
ROE?
Peers
50
S&P
59
16.7%STRONG
ROA?
Peers
50
S&P
85
14.0%STRONG
Cash Flow & Enterprise
FCF?$19.6M
Enterprise Value?$15.1M
Fundamentals ratios updated end of day