Spero Therapeutics, Inc. Common Stock

SPRONASDAQ • USD
1.07 USD
↘ 0.04 (3.60%)AT CLOSE (03:59 PM EDT)
1.07
↘ 0.01 (0.47%)
POST MARKET (AS OF 07:37 PM EDT)
Post Market
AS OF 07:37 PM EDT
1.07
↘ 0.01 (0.47%)
🔴Market: CLOSED

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $1.07 per share. Technical and fundamental signals converge bearish — technicals rate "Strong Sell" while fundamentals read "Sell". This is driven by a concerning Altman Z-Score in the distress zone, a weak Piotroski F-Score of 0/9, a bearish Death Cross on the long-term moving averages and bearish long-term moving average alignment. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Oct 26, 2026.

Open?$1.10
High?$1.11
Low?$1.06
Prev. Close?$1.11
Volume?513.9K
Avg. Volume?731.1K
VWAP?$1.08
Rel. Volume?0.70x
Bid / Ask
Bid?$1.07 × 100
Ask?$1.15 × 100
Spread?$0.08
Midpoint?$1.11
Valuation & Ratios
Market Cap?62.3M
Shares Out?58.2M
Float?42.1M
Float %?72.7%
P/E Ratio?8.44
P/B Ratio?1.41
EPS?$0.13
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
64.6M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookStrong Sell
Strong SellNeutralStrong Buy
Long-Term (Tide)?▼ Bearish(-3/3)
Medium-Term (Wave)?▼ Bearish(-3/3)
Short-Term (Ripple)?▼ Bearish(-3/3)
MA Alignment?Bearish Alignment
Full Technical Analysis →
Fundamental OutlookSell
Strong SellNeutralStrong Buy
F-Score?
3
Z-Score?
0
Momentum?
10
Short Sent.?
59
Piotroski F-Score?0/9Weak
Altman Z-Score?-5.63Distress
Confidence?51%Low
Full Fundamental Analysis →
Short InterestLow
Short % of Float?2.00%Low
Short Interest?840.5K
Days to Cover?1.5
Free Float42.1M
Avg Daily Volume558.5K
Settlement Date2026-10-15
Financial Health
Current Ratio?6.12Strong
Quick Ratio?6.12Strong
Cash Ratio?6.02Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
100/100
P/E?
Peers
100
S&P
97
8.4CHEAP▾
P/B?
Peers
100
S&P
89
1.41CHEAP▾
P/S?
Peers
100
S&P
81
1.33CHEAP▾
P/FCF?
Peers
100
S&P
97
3.2CHEAP▾
EV/EBITDA?
Peers
100
S&P
97
1.8CHEAP▾
EV/Sales?
Peers
100
S&P
97
0.25CHEAP▾
Returns & Efficiency
ROE?
Peers
50
S&P
59
16.7%STRONG▾
ROA?
Peers
50
S&P
85
14.0%STRONG▾
Cash Flow & Enterprise
FCF?$19.6M
Enterprise Value?$11.6M
Fundamentals ratios updated end of day