Spero Therapeutics, Inc. Common Stock

SPRONASDAQUSD
1.58 USD
0.01 (0.64%)AT CLOSE (11:59 AM EDT)
1.59
0.01 (0.44%)
POST MARKET (AS OF 07:56 PM EDT)
Post Market
AS OF 07:56 PM EDT
1.59
0.01 (0.44%)
🔴Market: CLOSED

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $1.58 per share. Technical and fundamental signals converge bearishtechnicals rate "Strong Sell" while fundamentals read "Sell". This is driven by a concerning Altman Z-Score in the distress zone, a weak Piotroski F-Score of 1/9, exceptional Return on Equity (28.8%) and a bearish Death Cross on the long-term moving averages. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Jul 17, 2026.

Open?$1.52
High?$1.64
Low?$1.50
Prev. Close?$1.57
Volume?1.2M
Avg. Volume?1.8M
VWAP?$1.59
Rel. Volume?0.68x
Bid / Ask
Bid?$1.48 × 1.9K
Ask?$1.81 × 100
Spread?$0.33
Midpoint?$1.65
Valuation & Ratios
Market Cap?90.9M
Shares Out?57.9M
Float?42.1M
Float %?72.7%
P/E Ratio?5.97
P/B Ratio?1.72
EPS?$0.26
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
90.9M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookStrong Sell
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bearish(-3/3)
Medium-Term (Wave)? Bearish(-2/3)
Short-Term (Ripple)? Bearish(-2/3)
MA Alignment?Mixed
Full Technical Analysis →
Fundamental OutlookSell
Strong SellNeutralStrong Buy
F-Score?
6
Z-Score?
10
Momentum?
50
Short Sent.?
51
Piotroski F-Score?1/9Weak
Altman Z-Score?0.94Distress
Confidence?59%Low
Full Fundamental Analysis →
Short InterestElevated
Short % of Float?6.80%Elevated
Short Interest?2.9M
Days to Cover?1.0
Free Float42.1M
Avg Daily Volume2.8M
Settlement Date2026-06-30
Financial Health
Current Ratio?10.50Strong
Quick Ratio?10.50Strong
Cash Ratio?10.23Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
100/100
P/E?
Peers
100
S&P
97
6.0CHEAP
P/B?
Peers
100
S&P
82
1.72CHEAP
P/S?
Peers
100
S&P
79
1.49CHEAP
P/FCF?
N/A
EV/EBITDA?
Peers
100
S&P
97
2.5CHEAP
EV/Sales?
Peers
100
S&P
97
0.57CHEAP
Returns & Efficiency
ROE?
Peers
50
S&P
78
28.8%STRONG
ROA?
Peers
50
S&P
97
25.8%STRONG
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$34.9M
Fundamentals ratios updated end of day