Spero Therapeutics, Inc. Common Stock

SPRONASDAQUSD
2.82 USD
0.16 (5.37%)AT CLOSE (11:59 AM EDT)
2.83
0.01 (0.39%)
POST MARKET (AS OF 07:44 PM EDT)
Post Market
AS OF 07:44 PM EDT
2.83
0.01 (0.39%)
🔴Market: CLOSED
Open?$3.00
High?$3.00
Low?$2.76
Prev. Close?$2.98
Volume?756.3K
Avg. Volume?695.6K
VWAP?$2.87
Rel. Volume?1.09x
Bid / Ask
Bid?$2.79 × 100
Ask?$2.94 × 100
Spread?$0.15
Midpoint?$2.87
Valuation & Ratios
Market Cap?163.3M
Shares Out?57.9M
Float?39.8M
Float %?70.6%
P/E Ratio?10.72
P/B Ratio?3.08
EPS?$0.26
Dividend?0.00%
Ex-Dividend?N/A

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $2.82 per share. The technical outlook is "Strong Buy" and the fundamental picture shows "Neutral". This is driven by a robust Altman Z-Score, a weak Piotroski F-Score of 1/9, exceptional Return on Equity (28.8%), a bullish Golden Cross on the moving averages and bullish moving average alignment. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Jun 5, 2026.

News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
163.3M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bullish(+3/3)
Medium-Term (Wave)? Bullish(+2/3)
Short-Term (Ripple)? Bearish(-2/3)
MA Alignment?Golden Alignment
Full Technical Analysis →
Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?
6
Z-Score?
100
Momentum?
50
Short Sent.?
45
Piotroski F-Score?1/9Weak
Altman Z-Score?8.08Safe
Confidence?46%Low
Full Fundamental Analysis →
Short InterestLow
Short % of Float?4.14%Low
Short Interest?1.6M
Days to Cover?2.6
Free Float39.8M
Avg Daily Volume630.5K
Settlement Date2026-05-15
Financial Health
Current Ratio?10.50Strong
Quick Ratio?10.50Strong
Cash Ratio?10.23Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
93/100
P/E?
Peers
100
S&P
94
10.7CHEAP
P/B?
Peers
100
S&P
55
3.08FAIR
P/S?
Peers
100
S&P
55
2.67CHEAP
P/FCF?
N/A
EV/EBITDA?
Peers
100
S&P
92
7.6CHEAP
EV/Sales?
Peers
100
S&P
80
1.75CHEAP
Returns & Efficiency
ROE?
Peers
50
S&P
78
28.8%STRONG
ROA?
Peers
50
S&P
97
25.8%STRONG
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$107.2M
Fundamentals ratios updated end of day