Spero Therapeutics, Inc. Common Stock

SPRONASDAQUSD
2.26 USD
0.24 (11.88%)AT CLOSE (11:59 AM EDT)
2.29
0.03 (1.28%)
POST MARKET (AS OF 07:59 PM EDT)
Post Market
AS OF 07:59 PM EDT
2.29
0.03 (1.28%)
🔴Market: CLOSED

Spero Therapeutics, Inc. Common Stock (SPRO) trades at $2.26 per share. The technical outlook is "Sell" and the fundamental picture shows "Neutral". This is driven by a robust Altman Z-Score, a weak Piotroski F-Score of 1/9, exceptional Return on Equity (28.8%) and a bullish Golden Cross on the moving averages. Valuation metrics suggest SPRO is trading at a discount to its peers, earning an "Attractively Valued" rating.

Technical & fundamental data as of Jun 26, 2026.

Open?$2.03
High?$2.33
Low?$2.01
Prev. Close?$2.02
Volume?2.2M
Avg. Volume?1.6M
VWAP?$2.22
Rel. Volume?1.43x
Bid / Ask
Bid?$2.21 × 100
Ask?$2.29 × 100
Spread?$0.08
Midpoint?$2.25
Valuation & Ratios
Market Cap?130.9M
Shares Out?57.9M
Float?39.8M
Float %?70.6%
P/E Ratio?8.59
P/B Ratio?2.47
EPS?$0.26
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
Employees
25
Market Cap
117.0M
Industry
PHARMACEUTICAL PREPARATIONS
Listed
2017-11-02
Address
675 MASSACHUSETTS AVENUE
CAMBRIDGE, MA 02139
Phone: 857-242-1600
Technical OutlookSell
Strong SellNeutralStrong Buy
Long-Term (Tide)? Bearish(-2/3)
Medium-Term (Wave)? Bearish(-2/3)
Short-Term (Ripple)? Bullish(+2/3)
MA Alignment?Mixed
Full Technical Analysis →
Fundamental OutlookNeutral
Strong SellNeutralStrong Buy
F-Score?
6
Z-Score?
98
Momentum?
50
Short Sent.?
50
Piotroski F-Score?1/9Weak
Altman Z-Score?4.88Safe
Confidence?46%Low
Full Fundamental Analysis →
Short InterestLow
Short % of Float?4.60%Low
Short Interest?1.8M
Days to Cover?2.3
Free Float39.8M
Avg Daily Volume813.4K
Settlement Date2026-06-15
Financial Health
Current Ratio?10.50Strong
Quick Ratio?10.50Strong
Cash Ratio?10.23Strong
Debt/Equity?0.00Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score
100/100
P/E?
Peers
100
S&P
97
8.6CHEAP
P/B?
Peers
100
S&P
65
2.47CHEAP
P/S?
Peers
100
S&P
63
2.14CHEAP
P/FCF?
N/A
EV/EBITDA?
Peers
100
S&P
97
5.3CHEAP
EV/Sales?
Peers
100
S&P
88
1.22CHEAP
Returns & Efficiency
ROE?
Peers
50
S&P
78
28.8%STRONG
ROA?
Peers
50
S&P
97
25.8%STRONG
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$74.8M
Fundamentals ratios updated end of day