10.21 USD
↗ 0.75 (7.93%)AT CLOSE (11:59 AM EDT)
Karyopharm Therapeutics Inc.
KPTINASDAQ • USD
10.15
↘ 0.06 (0.59%)
POST MARKET (AS OF 07:43 PM EDT)
Post Market
AS OF 07:43 PM EDT
10.15
↘ 0.06 (0.59%)
Market: CLOSED
Karyopharm Therapeutics Inc. (KPTI) trades at $10.21 per share. There is a divergence between signals — technical indicators rate "Strong Buy" but underlying fundamentals lean "Sell". This is driven by a concerning Altman Z-Score in the distress zone, a weak Piotroski F-Score of 2/9, exceptional Return on Equity (73.4%), a bullish Golden Cross on the moving averages and bullish moving average alignment. Valuation metrics suggest KPTI is trading at a discount to its peers, earning an "Attractively Valued" rating.
Technical & fundamental data as of Jun 26, 2026.
Open?$9.45
High?$10.25
Low?$9.43
Prev. Close?$9.46
Volume?3.2M
Avg. Volume?533.6K
VWAP?$9.81
Rel. Volume?6.04x
Bid / Ask
Bid?$7.91 × 100
Ask?$11.70 × 100
Spread?$3.79
Midpoint?$9.81
Valuation & Ratios
Market Cap?231.4M
Shares Out?22.7M
Float?18.0M
Float %?98.0%
P/E Ratio?N/A
P/B Ratio?-0.87
EPS?-$8.60
Dividend?0.00%
Ex-Dividend?N/A
News
Profile
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).
Employees
228
Market Cap
214.4M
Industry
PHARMACEUTICAL PREPARATIONS
Website
Listed
2013-11-06
Address
85 WELLS AVENUE
NEWTON, MA 02459
Phone: 617-658-0600
NEWTON, MA 02459
Phone: 617-658-0600
Technical OutlookStrong Buy
Strong SellNeutralStrong Buy
Long-Term (Tide)?▲ Bullish(+3/3)
Medium-Term (Wave)?▲ Bullish(+3/3)
Short-Term (Ripple)?▲ Bullish(+3/3)
MA Alignment?Golden Alignment
Full Technical Analysis →Fundamental OutlookSell
Strong SellNeutralStrong Buy
F-Score?12
Z-Score?0
Momentum?69
Short Sent.?10
Piotroski F-Score?2/9Weak
Altman Z-Score?-19.52Distress
Confidence?50%Low
Short InterestSqueeze Risk
Short % of Float?31.06%Squeeze Risk
Short Interest?5.6M
Days to Cover?16.8
Free Float18.0M
Avg Daily Volume332.6K
Settlement Date2026-06-15
Financial Health
Current Ratio?1.08Adequate
Quick Ratio?1.05Adequate
Cash Ratio?0.77Adequate
Debt/Equity?-0.84Low
ValuationATTRACTIVELY VALUEDvs 1 peers + S&P 500
Score100/100
P/E?N/A▾
P/B?-0.87CHEAP▾
S&P97
P/S?1.53CHEAP▾
Peers100
S&P78
P/FCF?N/A▾
EV/EBITDA?-4.4CHEAP▾
S&P97
EV/Sales?2.41CHEAP▾
Peers100
S&P69
Returns & Efficiency
ROE?73.4%STRONG▾
Peers50
S&P95
ROA?-148.4%WEAK▾
S&P3
Cash Flow & Enterprise
FCF?N/A
Enterprise Value?$364.9M
Fundamentals ratios updated end of day