After-hours trading runs 4:00 PM – 8:00 PM ET.
SPRB last traded at $46.36 after hours, down $0.30 (0.65%) from its regular-session close of $46.66.
📅 SPRB reported earnings on Nov 9, 2026 before the open, with an estimated EPS of $-5.68. SPRB earnings details →
Spruce Biosciences (SPRB) is trading at $46.36 after hours, down $0.30 (0.65%) from its regular-session close of $46.66.
SPRB is down 0.65% in after-hours trading. Moves in this session almost always follow something released after the 4:00 PM ET close — an earnings report, guidance, a filing, or news — and trade on far thinner volume than the regular session, so the size of the move can overstate what the market will settle on at the next open.
After-hours trading in SPRB on the NASDAQ runs from 4:00 PM to 8:00 PM ET on trading days, immediately after the regular session closes. Not every broker offers the full window, and liquidity thins sharply after about 6:30 PM ET.
SPRB reported earnings on Nov 9, 2026 before the open, with an estimated EPS of $-5.68. Earnings are the most common cause of a large after-hours move, since most companies report after the close.