52-Week High Breakout

Stocks that have broken above their 52-week high — a powerful momentum signal indicating new price discovery. — updated 2026-09-25

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Signal:bullish

Our models detected 25 equities meeting the criteria for a 52-week high breakout today, a signal historically associated with trend continuation to the upside. Leading the list is Moderna, Inc. Common Stock (MRNA), which is showing the primary signal alongside Triple MA Bull, ST Triple Bull, 52W Breakout, Near 52W High, RS New High, though internal indicators flag caution with an active RSI Overbought. Traders should look for volume confirmation before committing to this setup. Also noteworthy is Direxion Shares ETF Trust Direxion Daily AMD Bull 2X ETF (AMUU), triggering Triple MA Bull, ST Triple Bull, RSI Overbought, MFI Overbought, 52W Breakout, Near 52W High and carrying an RS Rating of 99. The complete list below is ranked by relative strength and market capitalization to surface the highest-conviction names.

25 Stocks
#TickerCompanySectorSignalsRSIMFIADXRS1M Perf
1MRNAModerna, Inc. Common StockHealthcare
76.179.360.199+29.0%
2AMUUDirexion Shares ETF Trust Direxion Daily AMD Bull 2X ETF—
72.384.425.899+70.3%
3IOVAIovance Biotherapeutics, Inc. Common StockHealthcare
74.467.956.099+31.9%
4SAIHSAIHEAT Limited Class A Ordinary SharesTechnology
75.853.241.199+31.6%
5CDNACareDx, Inc.Healthcare
79.374.748.499+27.0%
6GRALGRAIL, Inc. Common StockHealthcare
86.888.035.198+62.2%
7RCELAvita Medical, Inc. Common StockHealthcare
68.060.047.997+12.4%
8TBBBBBB Foods Inc.Consumer Staples
67.880.433.296+5.8%
9HQIHireQuest, Inc. Common Stock (DE)Industrials
76.290.435.896+15.2%
10AOUTAmerican Outdoor Brands, Inc. Common StockConsumer Discretionary
77.682.952.896+65.9%
11AVTAvnet, Inc.Technology
67.466.718.896+17.5%
12PRLBPROTO LABS, INC.Industrials
73.976.021.896+24.4%
13FLXSFlexsteel IndustriesConsumer Discretionary
72.048.718.795+9.6%
14MGLDThe Marygold Companies, Inc.Financials
84.399.733.095+83.8%
15IMAXImax CorpCommunication Services
66.254.524.194+4.3%
16FSEAFirst Seacoast Bancorp, Inc. Common StockFinancials
70.576.452.592+1.0%
17MTLSMaterialise NVTechnology
79.085.247.692+29.9%
18BBHVanEck Biotech ETF—
64.939.731.191+1.2%
19HELXFranklin Genomic Advancements ETF—
64.767.819.491+2.0%
20HTECROBO Global Healthcare Technology and Innovation ETF—
66.850.229.691+1.8%
21EKGFirst Trust Nasdaq Lux Digital Health Solutions ETF—
71.667.226.289+7.5%
22TMVDirexion Daily 20+ Year Treasury Bear 3X ETF—
68.169.818.188+14.6%
23FBLAFB Bancorp, Inc. Common StockFinancials
68.157.318.988+3.3%
24OPRTOportun Financial Corporation Common StockFinancials
66.577.934.585+14.8%
25TECHarbor Transformative Technologies ETF—
65.366.315.485+6.0%

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