54.85 USD
↗ 0.64 (1.18%)AFTER HOURS (AS OF Fri 07:53 PM EDT)
IONS Stock After Hours
Ionis Pharmaceuticals, Inc. Common Stock
IONSNASDAQ • USD
Market: CLOSED
After-hours trading runs 4:00 PM – 8:00 PM ET.
IONS last traded at $54.85 after hours, up $0.64 (1.18%) from its regular-session close of $54.21.
📅 IONS is expected to report earnings around Nov 4, 2026 before the open (estimated), with an estimated EPS of $-1.21. IONS earnings details →
IONS After Hours Chart
IONS After Hours News
Gap Analytics — 5-year history, 5% minimum gap
Over the past 5 years, IONS has had 11 qualifying gap events (gaps of 5% or more at the open) — 5 gap-ups and 6 gap-downs. Gap-ups averaged +8.8%, 40% have fully filled, median time to fill 3.5 trading days. Gap-downs averaged -10.2%, 33% have fully filled, median time to fill 13 trading days. Most recent: a -10.2% gap down 5 days ago, still unfilled. IONS has 1 unfilled gap from the past 60 days — a -10.2% gap down on Sep 8, 2026, currently 89% retraced. Average 20-trading-day return after a IONS gap up: +7.71%. After a gap down: -2.3%.
Gap Ups5 events
Fill Rate
40.0%
Avg Gap
8.8%
Avg 50% Fill
1d
Avg Fill
3.5d
Gap Downs6 events
Fill Rate
33.3%
Avg Gap
10.2%
Avg 50% Fill
3d
Avg Fill
13d
Avg Gap Fill by Timeframes
Gap Ups
| 1 day | 1 week | 2 week | 4 week | |
|---|---|---|---|---|
| fills 25% | 60% | 60% | 60% | 60% |
| fills 50% | 60% | 60% | 60% | 60% |
| fills 75% | 40% | 60% | 60% | 60% |
| fills 100% | 20% | 40% | 40% | 40% |
Gap Downs
| 1 day | 1 week | 2 week | 4 week | |
|---|---|---|---|---|
| fills 25% | 50% | 50% | 50% | 67% |
| fills 50% | 33% | 50% | 50% | 67% |
| fills 75% | 33% | 33% | 33% | 50% |
| fills 100% | 17% | 17% | 17% | 17% |
Active Unfilled Gaps (past 60 days)
5 days ago
2026-09-08
Gap %
-10.23%
Gap From
$58.09
% vs Current
+7.16%
retraced 89% to $57.43
Complete Gap History — 11 events
| Date | Gap From | Gap % | Status | Days to 50% | Days to Fill | % of Gap Filled After | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 day | 1 week | 2 week | 4 week | ||||||
| 5 days ago | $58.09 | -10.23% | Open | 1d | — | 89% | 89% | 89% | 89% |
| 2026-07-09 | $84.46 | -19.75% | Open | — | — | 15% | 15% | 15% | 15% |
| 2025-09-02 | $42.63 | +15.26% | Open | — | — | 0% | 0% | 0% | 0% |
| 2025-07-30 | $41.48 | +8.41% | Filled | 1d | 6d | 58% | 100% | 100% | 100% |
| 2025-04-30 | $29.81 | +6.61% | Open | 1d | — | 98% | 98% | 98% | 98% |
| 2025-02-19 | $31.95 | +7.98% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
| 2024-09-10 | $48.33 | -7.95% | Open | — | — | 3% | 3% | 3% | 3% |
| 2023-06-07 | $43.33 | -6.55% | Filled | 5d | 25d | 39% | 61% | 61% | 74% |
| 2022-08-03 | $37.18 | +5.49% | Open | — | — | 11% | 11% | 11% | 11% |
| 2022-01-31 | $31.68 | -10.54% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
| 2021-10-18 | $35.10 | -6.30% | Open | 13d | — | 10% | 10% | 10% | 100% |
Frequently Asked Questions
What is IONS's after-hours price?
Ionis Pharmaceuticals (IONS) is trading at $54.85 after hours, up $0.64 (1.18%) from its regular-session close of $54.21.
Why is IONS moving after hours?
IONS is up 1.18% in after-hours trading. Moves in this session almost always follow something released after the 4:00 PM ET close — an earnings report, guidance, a filing, or news — and trade on far thinner volume than the regular session, so the size of the move can overstate what the market will settle on at the next open.
When does IONS after-hours trading start and end?
After-hours trading in IONS on the NASDAQ runs from 4:00 PM to 8:00 PM ET on trading days, immediately after the regular session closes. Not every broker offers the full window, and liquidity thins sharply after about 6:30 PM ET.
Will IONS's after-hours move hold at the open?
An after-hours move that carries into the next session becomes an opening gap, and IONS's gap history is the best guide to what happens next: 40% of IONS gap-ups have fully filled, and 33% of gap-downs have filled over the past 5 years. Fill rates this high mean a large after-hours move is more often faded than extended.
When does IONS report earnings?
IONS is expected to report earnings around Nov 4, 2026 before the open (estimated), with an estimated EPS of $-1.21. Earnings are the most common cause of a large after-hours move, since most companies report after the close.