| Period | IONS | S&P 500 | NASDAQ | vs S&P |
|---|---|---|---|---|
| 1D | -5.11% | -0.21% | -0.16% | -4.90% |
| 5D | -7.57% | +0.20% | -0.09% | -7.76% |
| 1M | -12.26% | -1.73% | -2.99% | -10.53% |
| 3M | -30.78% | +2.48% | -2.00% | -33.25% |
| 6M | -27.87% | +15.08% | +19.40% | -42.96% |
| YTD | -35.43% | +11.15% | +15.48% | -46.58% |
| 1Y | -15.81% | +14.89% | +19.67% | -30.70% |
| 3Y | +19.82% | +71.16% | +91.02% | -51.34% |
| 5Y | +41.20% | +69.80% | +87.16% | -28.60% |