| Period | IONS | S&P 500 | NASDAQ | vs S&P |
|---|---|---|---|---|
| 1D | +6.41% | -0.36% | -1.20% | +6.77% |
| 5D | +3.09% | +0.59% | +0.76% | +2.49% |
| 1M | -32.32% | -1.16% | -4.21% | -31.16% |
| 3M | -50.43% | -2.37% | -6.85% | -48.07% |
| 6M | -60.64% | +2.81% | -3.08% | -63.46% |
| YTD | -63.52% | +10.42% | +10.89% | -73.95% |
| 1Y | -60.33% | +13.32% | +12.63% | -73.66% |
| 3Y | -40.13% | +67.55% | +76.16% | -107.68% |
| 5Y | -11.05% | +60.75% | +71.08% | -71.80% |