After-hours trading runs 4:00 PM – 8:00 PM ET.
MDGL last traded at $534.42 after hours, down $0.07 (0.01%) from its regular-session close of $534.49.
📅 MDGL is expected to report earnings around Nov 3, 2026 before the open (estimated), with an estimated EPS of $-0.86. MDGL earnings details →
Over the past 5 years, MDGL has had 26 qualifying gap events (gaps of 5% or more at the open) — 14 gap-ups and 12 gap-downs. Gap-ups averaged +23.3%, 64% have fully filled, median time to fill 4 trading days. Gap-downs averaged -8.2%, 83% have fully filled, median time to fill 10 trading days. Most recent: a -7.6% gap down on Jul 30, 2026, which filled in 20 trading days. Average 20-trading-day return after a MDGL gap up: +6.27%. After a gap down: +7.78%.
| 1 day | 1 week | 2 week | 4 week | |
|---|---|---|---|---|
| fills 25% | 79% | 93% | 93% | 93% |
| fills 50% | 57% | 79% | 79% | 79% |
| fills 75% | 43% | 71% | 71% | 71% |
| fills 100% | 21% | 57% | 57% | 57% |
| 1 day | 1 week | 2 week | 4 week | |
|---|---|---|---|---|
| fills 25% | 75% | 92% | 100% | 100% |
| fills 50% | 50% | 75% | 92% | 92% |
| fills 75% | 25% | 50% | 75% | 83% |
| fills 100% | 17% | 33% | 50% | 67% |
| Date | Gap From | Gap % | Status | Days to 50% | Days to Fill | % of Gap Filled After | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 day | 1 week | 2 week | 4 week | ||||||
| 2026-07-30 | $546.88 | -7.56% | Filled | 9d | 20d | 12% | 46% | 94% | 100% |
| 2026-05-06 | $502.47 | +5.72% | Filled | 2d | 4d | 39% | 100% | 100% | 100% |
| 2026-02-19 | $491.49 | -8.03% | Filled | 26d | 26d | 25% | 25% | 25% | 25% |
| 2025-08-05 | $312.11 | +12.14% | Open | 1d | — | 93% | 93% | 93% | 93% |
| 2025-07-16 | $311.14 | +5.15% | Filled | 5d | 6d | 0% | 100% | 100% | 100% |
| 2025-02-26 | $309.49 | +8.24% | Filled | 4d | 5d | 16% | 100% | 100% | 100% |
| 2025-01-27 | $328.14 | -7.36% | Filled | 2d | 2d | 44% | 100% | 100% | 100% |
| 2024-11-01 | $259.34 | +6.03% | Open | 1d | — | 78% | 78% | 78% | 78% |
| 2024-10-31 | $215.93 | +13.77% | Open | — | — | 26% | 26% | 26% | 26% |
| 2024-08-07 | $266.56 | -6.59% | Open | 10d | — | 0% | 0% | 75% | 75% |
| 2024-08-05 | $275.36 | -7.62% | Open | 1d | — | 63% | 94% | 94% | 94% |
| 2024-06-05 | $244.35 | -12.83% | Filled | 1d | 3d | 76% | 100% | 100% | 100% |
| 2024-05-07 | $235.57 | -5.76% | Filled | 1d | 11d | 63% | 63% | 100% | 100% |
| 2024-03-15 | $243.57 | +20.66% | Filled | 1d | 6d | 63% | 100% | 100% | 100% |
| 2024-02-26 | $236.54 | -6.57% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
| 2024-02-06 | $227.05 | -16.45% | Filled | 5d | 9d | 37% | 77% | 100% | 100% |
| 2023-11-14 | $146.00 | +5.23% | Open | — | — | 34% | 34% | 34% | 34% |
| 2023-09-29 | $151.69 | +6.14% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
| 2023-09-13 | $176.87 | +6.58% | Filled | 1d | 2d | 90% | 100% | 100% | 100% |
| 2023-09-11 | $196.58 | -5.79% | Filled | 3d | 54d | 22% | 72% | 72% | 72% |
| 2023-06-20 | $244.09 | +5.66% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
| 2023-04-18 | $256.55 | +5.24% | Filled | 1d | 33d | 60% | 60% | 60% | 60% |
| 2022-12-19 | $63.80 | +218.17% | Open | — | — | 8% | 8% | 8% | 8% |
| 2022-09-13 | $71.23 | +6.84% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
| 2022-07-08 | $77.35 | -6.46% | Filled | 1d | 21d | 51% | 51% | 51% | 100% |
| 2022-05-09 | $64.59 | -7.39% | Filled | 1d | 1d | 100% | 100% | 100% | 100% |
Madrigal Pharmaceuticals (MDGL) is trading at $534.42 after hours, down $0.07 (0.01%) from its regular-session close of $534.49.
MDGL is down 0.01% in after-hours trading. Moves in this session almost always follow something released after the 4:00 PM ET close — an earnings report, guidance, a filing, or news — and trade on far thinner volume than the regular session, so the size of the move can overstate what the market will settle on at the next open.
After-hours trading in MDGL on the NASDAQ runs from 4:00 PM to 8:00 PM ET on trading days, immediately after the regular session closes. Not every broker offers the full window, and liquidity thins sharply after about 6:30 PM ET.
An after-hours move that carries into the next session becomes an opening gap, and MDGL's gap history is the best guide to what happens next: 64% of MDGL gap-ups have fully filled, and 83% of gap-downs have filled over the past 5 years. Fill rates this high mean a large after-hours move is more often faded than extended.
MDGL is expected to report earnings around Nov 3, 2026 before the open (estimated), with an estimated EPS of $-0.86. Earnings are the most common cause of a large after-hours move, since most companies report after the close.