Opportunity Scan

Diamonds in the Rough

Cross-referencing fundamental value against technical exhaustion to isolate beaten-down XBI constituents that screen cheap and oversold. The bottom-right quadrant — high earnings yield, low RSI — is the prime hunting ground, especially where money flow (MFI) shows quiet accumulation despite the falling price.

50 in diamond zone152 scored

Educational screen, not investment advice. “Diamond” classification is a mechanical valuation-vs-RSI split around the cohort median earnings yield and an RSI of 50.

Alpha Quadrant — Valuation × Technical Exhaustion

X = earnings yield (cheaper right) · Y = RSI 14 (more oversold lower) · bubble = market cap · color = money flow.

Accumulation (MFI ≥ 55)Neutral flowDistribution (MFI ≤ 45)Diamond-zone ring
◆ Diamond in the RoughCheap + oversold. Deep value in a technically exhausted state — the prime target.
Fairly Valued WinnerCheap + extended. Strong action backed by earnings, but late for new entries.
Value TrapExpensive + beaten down. Falling yet still richly valued — structurally suspect.
Momentum DarlingExpensive + extended. Crowded leaders with mean-reversion risk.

Diamond Candidates

Ranked by a composite of earnings yield, ROIC, oversold RSI, recent weakness, and improving money flow.

#
1IRWDIronwood Pharmaceuticals, Inc. - Class A78.926.14%1.3837-18.20%50distress
2ABUSArbutus Biopharma Corporation Common Stock67.718.22%0.5538-13.40%26safe
3INCYIncyte Genomics Inc56.59.00%0.3348-7.28%53safe
4RIGLRigel Pharmaceuticals Inc. (New)56.49.77%0.9753+0.54%68safe
5EXELExelixis Inc50.46.11%0.9971+13.81%66safe
6ADMAADMA Biologics, Inc.49.28.61%0.4258+10.44%67safe
7NRIXNurix Therapeutics, Inc. Common stock47.914.02%0.2958+6.65%75safe
8ALNYAlnylam Pharmaceuticals, Inc.45.13.36%0.2742-9.12%51safe
9ACADAcadia Pharmaceuticals Inc.45.02.77%0.1036-19.07%48safe
10NBIXNeurocrine Biosciences Inc41.25.38%0.9050+3.00%40safe
11MDXGMiMedx Group, Inc40.11.92%0.0530-18.71%22safe
12HALOHalozyme Therapeutics, Inc.39.64.01%0.9674+12.04%71safe
13KRYSKrystal Biotech, Inc. Common Stock38.92.19%0.1838-8.88%37safe
14UTHRUnited Therapeutics Corp38.36.02%0.2969+24.28%56safe
15QUREuniQure N.V.37.7-15.25%-0.2528-47.12%60distress

Short-Squeeze Watch

Constituents with the highest composite squeeze score — heavy short interest meeting price support.

#
1AVBPArriVent BioPharma, Inc. Common Stock91.925.21%11.25-29.86%critical
2RLAYRelay Therapeutics, Inc. Common Stock87.429.66%12.59+0.50%critical
3CRVSCorvus Pharmaceuticals, Inc.87.125.30%13.31-15.49%critical
4ZBIOZenas BioPharma, Inc. Common Stock86.838.32%15.48-8.95%critical
5INBXInhibrx Biosciences, Inc. Common Stock86.435.62%11.82-8.79%critical
6TYRATyra Biosciences, Inc. Common Stock86.426.23%8.83-11.74%critical
7SPRYARS Pharmaceuticals, Inc. Common Stock85.943.26%16.10-4.28%critical
8IBRXImmunityBio, Inc. Common Stock85.631.42%8.88-3.29%critical
9CELCCelcuity Inc. Common Stock85.627.57%11.03-18.16%critical
10ORICOric Pharmaceuticals, Inc. Common Stock84.127.01%9.85-0.38%critical
11SLSSELLAS Life Sciences Group, Inc. Common Stock83.927.66%9.45+0.96%critical
12IMVTImmunovant, Inc. Common Stock83.520.10%9.64-16.95%critical

Market cap, valuation, and short-interest metrics are joined to the latest XBI holdings snapshot; each ticker links to its full quote and analysis page.