Diamonds in the Rough
Cross-referencing fundamental value against technical exhaustion to isolate beaten-down XBI constituents that screen cheap and oversold. The bottom-right quadrant — high earnings yield, low RSI — is the prime hunting ground, especially where money flow (MFI) shows quiet accumulation despite the falling price.
Educational screen, not investment advice. “Diamond” classification is a mechanical valuation-vs-RSI split around the cohort median earnings yield and an RSI of 50.
Alpha Quadrant — Valuation × Technical Exhaustion
X = earnings yield (cheaper right) · Y = RSI 14 (more oversold lower) · bubble = market cap · color = money flow.
Diamond Candidates
Ranked by a composite of earnings yield, ROIC, oversold RSI, recent weakness, and improving money flow.
| # | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | IRWD | Ironwood Pharmaceuticals, Inc. - Class A | 78.9 | 26.14% | 1.38 | 37 | -18.20% | 50 | distress |
| 2 | ABUS | Arbutus Biopharma Corporation Common Stock | 67.7 | 18.22% | 0.55 | 38 | -13.40% | 26 | safe |
| 3 | INCY | Incyte Genomics Inc | 56.5 | 9.00% | 0.33 | 48 | -7.28% | 53 | safe |
| 4 | RIGL | Rigel Pharmaceuticals Inc. (New) | 56.4 | 9.77% | 0.97 | 53 | +0.54% | 68 | safe |
| 5 | EXEL | Exelixis Inc | 50.4 | 6.11% | 0.99 | 71 | +13.81% | 66 | safe |
| 6 | ADMA | ADMA Biologics, Inc. | 49.2 | 8.61% | 0.42 | 58 | +10.44% | 67 | safe |
| 7 | NRIX | Nurix Therapeutics, Inc. Common stock | 47.9 | 14.02% | 0.29 | 58 | +6.65% | 75 | safe |
| 8 | ALNY | Alnylam Pharmaceuticals, Inc. | 45.1 | 3.36% | 0.27 | 42 | -9.12% | 51 | safe |
| 9 | ACAD | Acadia Pharmaceuticals Inc. | 45.0 | 2.77% | 0.10 | 36 | -19.07% | 48 | safe |
| 10 | NBIX | Neurocrine Biosciences Inc | 41.2 | 5.38% | 0.90 | 50 | +3.00% | 40 | safe |
| 11 | MDXG | MiMedx Group, Inc | 40.1 | 1.92% | 0.05 | 30 | -18.71% | 22 | safe |
| 12 | HALO | Halozyme Therapeutics, Inc. | 39.6 | 4.01% | 0.96 | 74 | +12.04% | 71 | safe |
| 13 | KRYS | Krystal Biotech, Inc. Common Stock | 38.9 | 2.19% | 0.18 | 38 | -8.88% | 37 | safe |
| 14 | UTHR | United Therapeutics Corp | 38.3 | 6.02% | 0.29 | 69 | +24.28% | 56 | safe |
| 15 | QURE | uniQure N.V. | 37.7 | -15.25% | -0.25 | 28 | -47.12% | 60 | distress |
Short-Squeeze Watch
Constituents with the highest composite squeeze score — heavy short interest meeting price support.
| # | |||||||
|---|---|---|---|---|---|---|---|
| 1 | AVBP | ArriVent BioPharma, Inc. Common Stock | 91.9 | 25.21% | 11.25 | -29.86% | critical |
| 2 | RLAY | Relay Therapeutics, Inc. Common Stock | 87.4 | 29.66% | 12.59 | +0.50% | critical |
| 3 | CRVS | Corvus Pharmaceuticals, Inc. | 87.1 | 25.30% | 13.31 | -15.49% | critical |
| 4 | ZBIO | Zenas BioPharma, Inc. Common Stock | 86.8 | 38.32% | 15.48 | -8.95% | critical |
| 5 | INBX | Inhibrx Biosciences, Inc. Common Stock | 86.4 | 35.62% | 11.82 | -8.79% | critical |
| 6 | TYRA | Tyra Biosciences, Inc. Common Stock | 86.4 | 26.23% | 8.83 | -11.74% | critical |
| 7 | SPRY | ARS Pharmaceuticals, Inc. Common Stock | 85.9 | 43.26% | 16.10 | -4.28% | critical |
| 8 | IBRX | ImmunityBio, Inc. Common Stock | 85.6 | 31.42% | 8.88 | -3.29% | critical |
| 9 | CELC | Celcuity Inc. Common Stock | 85.6 | 27.57% | 11.03 | -18.16% | critical |
| 10 | ORIC | Oric Pharmaceuticals, Inc. Common Stock | 84.1 | 27.01% | 9.85 | -0.38% | critical |
| 11 | SLS | SELLAS Life Sciences Group, Inc. Common Stock | 83.9 | 27.66% | 9.45 | +0.96% | critical |
| 12 | IMVT | Immunovant, Inc. Common Stock | 83.5 | 20.10% | 9.64 | -16.95% | critical |
Market cap, valuation, and short-interest metrics are joined to the latest XBI holdings snapshot; each ticker links to its full quote and analysis page.