Premarket Movers

Premarket stock movers, including top gainers, losers, and most active stocks before regular market hours.
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2026-08-17

Today's Premarket Market Analysis

TODAY, 8:00a ET: Small-cap biotech and tech dominate premarket action amid heavy volume and clinical trial misses. IPST is surging +182% on massive relative volume; IVF follows with a +167% jump. EYPT is gapping down -63% after its lead drug candidate missed the primary endpoint in a Phase 3 wet AMD trial.(more...)

Tape Overview

The premarket session shows a bifurcated tone as speculative small-caps attract massive volume while clinical failures weigh on the biotech sector.

Top Mover: IPST — [Surging on massive relative volume]

IP Strategy Holdings, Inc. (IPST) is gapping up 182.4% on 25.3M shares, representing a 465x surge over its historical volume norm. This move lacks a fresh news catalyst, suggesting a high-velocity momentum play or low-float squeeze.

Top Loser: EYPT — [Phase 3 clinical trial failure]

EyePoint, Inc. (EYPT) plummeted -63.0% after its DURAVYU treatment failed to meet the primary endpoint in the LUGANO Phase 3 trial for wet AMD. Management noted the data was confounded by an asymmetric cohort experiencing unrelated vision loss, but the market is pricing in significant clinical risk.

Also Moving

uCloudlink Group Inc. (UCL) climbed 56.8% following the announcement of a $2 million share repurchase program. Meanwhile, INVO Fertility, Inc. (IVF) is up 167.1% on 48.3M shares, appearing as a top signal on unusual volume scanners alongside IPST.

Broader Context

Traders should monitor if the momentum in micro-cap names spills over into the broader market or if the EYPT failure triggers a wider de-risking across the biotech sector.

Show per section:
10s
Data last updated: Today at 8:20 AM EDT

Premarket GainersGainers

%ChgLastSymbCompanyVolume
+242%
7.46
IP Strategy Holdings, Inc. Common Stock32869k
+150%
2.42
INVO Fertility, Inc. Common Stock50371k
+50%
1.46
TruGolf Holdings, Inc. Class A Common Stock17375k
+32%
4.02
My Size, Inc5368k
+26%
2.86
Super League Enterprise, Inc. Common Stock12674k
+22%
4.59
Quantum Biopharma Ltd. Class B Subordinate Voting Shares366k
+19%
4.02
OmniAb, Inc. Common Stock5822k
+19%
1.60
Freightos Limited Ordinary shares2722k
+19%
4.29
Expion360 Inc. Common Stock3701k
+16%
5.83
FiEE, Inc Common Stock1271k

Premarket LosersLosers

%ChgLastSymbCompanyVolume
-64%
5.30
EyePoint, Inc. Common Stock2012k
-28%
3.27
Apimeds Pharmaceuticals US, Inc.1342k
-26%
5.66
Greenpro Capital Corp. Common Stock143k
-19%
5.24
Akanda Corp. Common Shares368k
-15%
1.90
9F Inc. American Depositary Shares5501k
-9.4%
3.98
Enovix Corporation Common Stock636k
-9.4%
3.92
China SXT Pharmaceuticals, Inc. Class A Ordinary Shares132k
-9.3%
2.35
Onfolio Holdings Inc. Common Stock386k
-7.9%
2.77
DEFSEC Technologies Inc. Common Stock5923k
-7.9%
2.40
Sidus Space, Inc. Class A Common Stock426k

Premarket ActivesActives

%ChgLastSymbCompanyVolume
+4.1%
1707.01
Sandisk Corporation Common Stock933k
+3.1%
1001.47
Micron Technology, Inc.1418k
+0.5%
307.44
Apple Inc.2558k
+0.0%
139.97
Space Exploration Technologies Corp. Class A Common Stock3629k
+0.7%
226.78
Nvidia Corp1318k
-0.5%
512.52
Advanced Micro Devices511k
+242%
7.46
IP Strategy Holdings, Inc. Common Stock32869k
+3.8%
172.60
SK hynix Inc. American Depositary Shares1394k
+1.1%
103.71
Intel Corp2207k
-0.4%
587.39
Meta Platforms, Inc. Class A Common Stock369k

Premarket Unusual VolumeUnusual Volume

%ChgLastSymbCompanyVolume
+242%
7.46
IP Strategy Holdings, Inc. Common Stock32869k
+26%
2.86
Super League Enterprise, Inc. Common Stock12674k
+150%
2.42
INVO Fertility, Inc. Common Stock50371k
-26%
5.66
Greenpro Capital Corp. Common Stock143k
+50%
1.46
TruGolf Holdings, Inc. Class A Common Stock17375k
+32%
4.02
My Size, Inc5368k
+19%
4.29
Expion360 Inc. Common Stock3701k
-28%
3.27
Apimeds Pharmaceuticals US, Inc.1342k
+19%
4.02
OmniAb, Inc. Common Stock5822k
-2.4%
1.83
RenX Enterprises Corp. Common Stock307k

Premarket GainersGainers

%ChgLastSymbCompanyVolume
+242%
7.46
IP Strategy Holdings, Inc. Common Stock32869k
+150%
2.42
INVO Fertility, Inc. Common Stock50371k
+50%
1.46
TruGolf Holdings, Inc. Class A Common Stock17375k
+32%
4.02
My Size, Inc5368k
+26%
2.86
Super League Enterprise, Inc. Common Stock12674k
+22%
4.59
Quantum Biopharma Ltd. Class B Subordinate Voting Shares366k
+19%
4.02
OmniAb, Inc. Common Stock5822k
+19%
1.60
Freightos Limited Ordinary shares2722k
+19%
4.29
Expion360 Inc. Common Stock3701k
+16%
5.83
FiEE, Inc Common Stock1271k

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Premarket FAQs

Q: When does premarket open?
A: Premarket trading sessions start weekdays around 4:00 am EST and last until the market open, which is 9:30 am EST.
Q: Can you trade options premarket?
A: Options trading during premarket hours is generally not available. Options markets typically operate only during regular trading hours.
Q: How to trade premarket?
A: Most brokerages offer trading during premarket and after hours. Some popular examples are Robinhood, TD Ameritrade and E*Trade. It's usually best to trade with limit orders during the premarket, due to lower trading volumes.

⏰ Premarket Trading Hours by Brokerage

BrokeragePremarket Hours (ET)Notes
Interactive Brokers4:00 a.m. – 9:30 a.m.IBKR Pro from 4:00 a.m.; IBKR Lite from 7:00 a.m.
Webull4:00 a.m. – 9:30 a.m.Full extended hours available
Moomoo4:00 a.m. – 9:30 a.m.Extensive early access
TradeZero4:00 a.m. – 9:30 a.m.Full early access from 4:00 a.m.
Charles Schwab7:00 a.m. – 9:25 a.m.Orders may be placed after 8:05 p.m. the prior day
Fidelity7:00 a.m. – 9:28 a.m.Short sale orders allowed from 8:00 a.m.
E*TRADE7:00 a.m. – 9:30 a.m.Limit orders allowed from 7:00 a.m.
Merrill Edge7:00 a.m. – 9:30 a.m.Standard premarket access
Robinhood7:00 a.m. – 9:30 a.m.Extended hours trading enabled
Firstrade8:00 a.m. – 9:25 a.m.Shorter premarket window
Ally Invest8:00 a.m. – 9:30 a.m.Standard premarket access
TradeStation8:00 a.m. – 9:30 a.m.Premarket begins at 8:00 a.m.
Public8:00 a.m. – 9:30 a.m.Premarket trading supported
SoFi Invest9:00 a.m. – 9:30 a.m.Very limited premarket access
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